Different Ways To Achieve The Same Goal

NASA’s Juno Spacecraft Completes Flyby over Jupiter’s Great Red Spot

NASA’s Juno mission completed a close flyby of Jupiter and its Great Red Spot on July 10, during its sixth science orbit.

All of Juno’s science instruments and the spacecraft’s JunoCam were operating during the flyby, collecting data that are now being returned to Earth. Juno’s next close flyby of Jupiter will occur on Sept. 1.

Raw images from the spacecraft’s latest flyby will be posted in coming days.

“For generations people from all over the world and all walks of life have marveled over the Great Red Spot,” said Scott Bolton, principal investigator of Juno from the Southwest Research Institute in San Antonio. “Now we are finally going to see what this storm looks like up close and personal.”

The Great Red Spot is a 10,000-mile-wide (16,000-kilometer-wide) storm that has been monitored since 1830 and has possibly existed for more than 350 years. In modern times, the Great Red Spot has appeared to be shrinking.

Juno reached perijove (the point at which an orbit comes closest to Jupiter’s center) on July 10 at 6:55 p.m. PDT (9:55 p.m. EDT). At the time of perijove, Juno was about 2,200 miles (3,500 kilometers) above the planet’s cloud tops. Eleven minutes and 33 seconds later, Juno had covered another 24,713 miles (39,771 kilometers), and was passing directly above the coiling crimson cloud tops of the Great Red Spot.

The spacecraft passed about 5,600 miles (9,000 kilometers) above the clouds of this iconic feature.

On July 4 at 7:30 p.m. PDT (10:30 p.m. EDT), Juno logged exactly one year in Jupiter orbit, marking 71 million miles (114.5 million kilometers) of travel around the giant planet.

Juno launched on Aug. 5, 2011, from Cape Canaveral, Florida. During its mission of exploration, Juno soars low over the planet’s cloud tops – as close as about 2,100 miles (3,400 kilometers). During these flybys, Juno is probing beneath the obscuring cloud cover of Jupiter and studying its auroras to learn more about the planet’s origins, structure, atmosphere and magnetosphere.

Early science results from NASA’s Juno mission portray the largest planet in our solar system as a turbulent world, with an intriguingly complex interior structure, energetic polar aurora, and huge polar cyclones.

JPL manages the Juno mission for the principal investigator, Scott Bolton, of Southwest Research Institute. The Juno mission is part of the New Frontiers Program managed by NASA’s Marshall Space Flight Center in Huntsville, Alabama, for the Science Mission Directorate.

Lockheed Martin Space Systems, Denver, built the spacecraft. JPL is a division of Caltech in Pasadena

A special organic dye, Nile Red in different solvents.

From left to right I dissolved equal amounts of Nile Red (a dye) in different solvents. The solvents were: methanol, diisopropyl ether, hexane, n-propanol, tetrahydrofuran, toluene, ethanol, acetone.

Depending on the solvents polarity, the dye dissolved to give different colored solutions (upper image), this is called solvatochromism. It is the ability of a chemical substance to change color due to a change in solvent polarity.

Under UV light, these solutions emitted different colors (bottom pics), this is called solvatofluorescence. The emission and excitation wavelength both shift depending on solvent polarity, so it fluoresces with different color depending on the solvent what it’s dissolved in.

Nile Red is a quite expensive dye, which costs a bit over 1000 USD/gram, therefore I had to make it. The purification of the raw material was posted HERE. 

To help the blog, donate to Labphoto through Patreon: https://www.patreon.com/labphoto

A Brand-New Human Organ Has Been Identified

Your body now has an extra organ — meet the mesentery.

A mighty membrane that twists and turns through the gut is starting the new year with a new classification: the structure, called the mesentery, has been upgraded to an organ.

Scientists have known about the structure, which connects a person’s small and large intestines to the abdominal wall and anchors them in place, according to the Mayo Clinic. However, until now, it was thought of as a number of distinct membranes by most scientists. Interestingly, in one of its earliest descriptions, none other than Leonardo da Vinci identified the membranes as a single structure, according to a recent review.

For International Women’s Day, here are 12 women from chemistry history: wp.me/p4aPLT-2ra and 12 from chemistry present: wp.me/p4aPLT-5w7

Hepatitis B in a Laboratory!! #serology #infection #liver #hepatitis #medicine #medstudent #medstudynotes #virus #medschool #microbiology #pathology https://www.instagram.com/p/BrIYa-LheyH/?utm_source=ig_tumblr_share&igshid=lqm0j92yobw0

Superconducting Bismuth Is Real, and It's Forcing Us to Rethink the Nature of Superconductivity

A Nobel Prize-winning theory has been challenged.

Bismuth is one of the weirdest-looking elements on the Periodic Table, but its internal properties just got even stranger. Scientists have discovered that at a fraction of a degree above absolute zero (-273.15°C), bismuth becomes a superconductor - a material that can conduct electricity without resistance.

According to the current theory of superconductivity, that doesn’t make a whole lot of sense, because for 40 years now, scientists have assumed that superconducting materials must be abundant in free-flowing mobile electrons. But in bismuth, there’s just one mobile electron for every 100,000 atoms.

“In general, compounds that exhibit superconductivity have roughly one mobile electron per atom,” Srinivasan Ramakrishnan from the Tata Institute of Fundamental Research in India explained to Chemistry World.

“However, in bismuth, one mobile electron is shared by 100,000 atoms – since [the] carrier density is so small, people did not believe bismuth will superconduct.”

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Thyroid function tests

Standard Tests

TSH levels

Free T4 (fT4) levels

Measurements of total T4 + T3 used to be common however detects both bound and free T3 + T4

Elevated total T4 may occur in healthy individuals if there is an increase in binding protein concentrations

Reliable tests now exist for free T4 + T3

T3 = 3.9-6.7 pmol/L

T4 = 12-22 pmol/L

Thyroid-stimulating hormone

Produced by the pituitary gland, not the thyroid, however:

TSH levels are controlled by negative feedback – can be indication of thyroid function (changes in T3+T4 will result in changes in TSH to try compesate)

TSH levels greatly elevated in hypothyroidism – >10 fold increase over reference values

More sensitive marker than decreased fT4 - increased TSH occurs before fT4 decreases

TSH levels greatly supressed in hyperthyroidism

Low concentrations can also occur in non-thyroidal illness

TSH measurement is the first-line test of thyroid function.

Free T4 + T3 Measurements

Desirable as free hormone is clinically relevant

Total levels can change under conditions that alter thyroxine-binding globulin (TBG) levels e.g. pregnancy

Large changes in TBG may still affect fT4 + fT3 levels

fT3 levels often normal in hypothyroidism

fT3 levels usually raised more than fT4 levels in hyperthyroidism

Unless complicated by an illness effecting conversion of T4 to T3

Therefore: – fT4 levels are a better indication of hypothyroidism

fT3 levels are a better indication of hyperthyroidism

WATCH: A Macro Timelapse Highlights the Micro Movements of Spectacularly Colored Coral [video]

Estrogen Alters Memory Circuit Function in Women with Gene Variant

Fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene, NIMH scientists have discovered. Brain scans revealed altered circuit activity linked to changes in the sex hormone in women with the gene variant while they performed a working memory task.

(Image caption: Both PET scans (left) and fMRI scans (right) showed the same atypical activation (yellow) in the brain’s memory hub, or hippocampus, in response to estrogen in women performing a working memory task – if they carried a uniquely human version of the BDNF gene. Activity in this area is typically suppressed during working memory. Picture shows PET and fMRI data superimposed over anatomical MRI image)

The findings may help to explain individual differences in menstrual cycle and reproductive-related mental disorders linked to fluctuations in the hormone. They may also shed light on mechanisms underlying sex-related differences in onset, severity, and course of mood and anxiety disorders and schizophrenia. The gene-by-hormone interaction’s effect on circuit function was found only with one of two versions of the gene that occurs in about a fourth of white women.

Drs. Karen Berman, Peter Schmidt, Shau-Ming Wei, and colleagues, of the NIMH Intramural Research Program, report on this first such demonstration in women April 18, 2017 in the journal Molecular Psychiatry.

Prior to the study, there was little evidence from research on the human brain that might account for individual differences in cognitive and behavioral effects of sex hormones. For example, why do some women develop postpartum depression and others do not – in response to the same hormone changes? Why do some women report that estrogen replacement improved their memory, whereas large studies of postmenopausal estrogen therapy show no overall improvement in memory performance?

Evidence from humans has also been lacking for the neural basis of stark sex differences in prevalence and course of mental disorders that are likely related to sex hormones. For example, why are there higher rates of mood disorders in females and higher rates of ADHD in males – or later onset of schizophrenia in females?

In seeking answers to these questions, the researchers focused on working memory, a well-researched brain function often disturbed in many of these disorders. It was known that working memory is mediated by a circuit from the brain’s executive hub, the prefrontal cortex, to its memory hub, the hippocampus. Notably, hippocampus activity is typically suppressed during working memory processing.

Following-up on a clue from experiments in mice, the NIMH team hypothesized that estrogen tweaks circuit function by interacting with a uniquely human version of the gene that codes for brain derived neurotrophic factor (BDNF), a pivotal chemical messenger operating in this circuit. To find out, the researchers experimentally manipulated estrogen levels in healthy women with one or the other version of the BDNF gene over a period of months. Researchers periodically scanned the women’s brain activity while they performed a working memory task to see any effects of the gene-hormone interaction on circuit function.

The researchers first scanned 39 women using PET (positron emission tomography) and later confirmed the results in 27 women using fMRI (functional magnetic resonance imaging). Both pegged atypical activity in the hippocampus to the interaction. Turning up the same findings using two types of neuroimaging strengthens the case for the accuracy of their observations, say the researchers. Such gene-hormone interactions affecting thinking and behavior are consistent with findings from animal studies and are suspect mechanisms conferring risk for mental illness, they add.

history meme (french edition) → 7 inventions/achievements (2/7) the first vaccine for rabies by Louis Pasteur & Émile Roux

“Pasteur had, in the early 1880s, a vaccine for rabies, but he was a chemist and not a licensed physician, and potentially liable if he injured or killed a human being. In early july 1885, Joseph Meister, a nine year-old-boy, had been badly mauled and bitten by a rabid dog (…). Pasteur injected young Meister with his rabies vaccine: the boy did not develop rabies and recovered fully from his injuries. Pasteur became a hero, and the Parisian Institue which came to be named in his honour, and of which he was the first director, became the global prototype bacteriological and immunological research institute. By demonstrating beyond doubt that many diseases were transmitted by bacteria and could be prevented from becoming active by pasteurization techniques, Pasteur indeed changed the course of history.” – G. L. Geison, The Private Science of Louis Pasteur.