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Other physical symptoms were definitely something to consider while thinking about it! We know that their human forms do fall ill to whatever risks are there, such as Vex's old "geezer" form to be weaker.

The headcannon was primarily based off of appearances, though. I would like to imagine that Aja would do her best to take care of herself, despite being quite reckless most of the time! I also think that Mothership would've been aware of some of the conditions, and that's why Aja first appears with full-coverage clothing when her human form first appeared (idk Mothership being motherly is great).

The idea just resignated with me since I noticed the way people with albinism (or traits commonly associated with albinism) are often negatively treated in media; either perceived as evil, butt of jokes, etc,. So to have a kind, strong, and lively protagonist with these characteristics, it can be something that's important to someone, even if it's not explicitly said nor canon.

So short answer: yes

I always headcanoned that Aja's human form is genetically related to Krel's, but her's just has albinism.

I say this mainly because they do have similar facial features, such as their noses, large smiles, eye shape (large, a bit more wide-set), and slightly wavy hair texture.

But Aja does have many visual traits of albinism, such as her extremely light hair, skin, and eyes.