These are more my personal thoughts / headcanons / lore building for Sasuke, since Kishi is just ... really really fucking poor with details and loves to just throw curve-balls where they don't make sense. ( aka I still think the twist with Itachi came from nowhere given how we were never shown anything on the Uchihas being discriminated against before the 'truth' of the massacre; aside from them living in a compound and the police force being exclusively Uchiha. And even then, those weren't really foreshadowing. ) A lot are expanded upon from 'canon'.
The Uchiha Compound was located up against the outskirts of the village, removed notably from the rest of the village. Therefore when Sasuke started attending the Academy, he had to get up particularly early in order to make his way there on time; since it was significantly further away.
While villagers didn't actively keep from selling to the Uchiha in the marketplace, it was more begrudgingly. At some points, depending on the merchant, prices were even raised when they noticed it was an Uchiha they were selling to.
Most parents kept their kid away from Uchiha children; as they felt like the close proximity would rub off a 'curse' onto them.
Whispered stereotypes among the villagers were 'blood thirsty' and 'attack dogs'; many saw the Uchiha as harbingers of violence, and didn't believe they were capable of anything but such.
Piggybacking off of that, it was unspoken that the only career path for an Uchiha was either training to be a ninja or training to join the police force ( or both ). If you aspired to do anything else such as become a school teacher, the obstacles that stood due to the stereotypes and discrimination made it virtually impossible, although they'd always reassure that it wasn't because of blood.
Fire jutsu is seen as taboo to teach young genin not just because of the mastery of chakra that it requires, but because it's a staple jutsu in the usual Uchiha's repertoire, and due to that there's a stigma surrounding fire based jutsu in the Leaf.
Following the genocide, many treated Sasuke with a distant sort of pity; not intervening to help him in any significant way, but also silently toting him as 'one of the good ones', especially with him becoming the most promising genin of his class. Sasuke received a lot of distant praise, but it was always conditional, ready to be revoked at any wrong move.