A Pure Philosopher Has No Other Touchstone For Truth Than Our Natural Understanding, Not Theology.

A pure philosopher has no other touchstone for truth than our natural understanding, not theology.

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8 months ago

If you're aware of an annoying pattern you keep doing, you've already won half the battle.

being self aware suuuucks like yeah this thought pattern/behavior is stupid and pointless and a symptom. i know this. [does it anyways

1 year ago

people don't change as much as you think they do. they mostly become what they already were.

8 months ago

The origins of modern genetics. From Mendel's principles of heredity, by W. Bateson.

The Origins Of Modern Genetics. From Mendel's Principles Of Heredity, By W. Bateson.
The Origins Of Modern Genetics. From Mendel's Principles Of Heredity, By W. Bateson.
The Origins Of Modern Genetics. From Mendel's Principles Of Heredity, By W. Bateson.

(cont.) These F₂ plants were again allowed to fertilise themselves and the offspring of each plant was separately sown. It was then found that the offspring, F₃, of the recessives consisted entirely of recessives. Further generations bred from these recessives again produced recessives only, and therefore the recessives which appeared in F₂ are seen to be pure to the recessive character, namely, in the case we are considering, to dwarfness. But the tall F₂ dominants when tested by a study of their offspring (F₃), instead of being all alike (as the dwarfs or recessives were), proved to be of two kinds, viz. (a) Plants which gave a mixed F₃ consisting of both talls and dwarfs, the proportion showing again an average of three talls to one dwarf. (b) Plants which gave talls only and are thus pure to tallness. The ratio of the impure (a) plants to the pure (b) plants was as 2 to 1. The whole F₂ generation therefore, formed by self-fertilisation of the original hybrid consists of three kinds of plants: 25% pure dominants, 50% impure dominants, 25% pure recessives. Or three dominants : one recessive.

8 months ago

Acne is all like, "Hey, you don't have any meetings? That's cool. Well, I'm going to take a leave of absence until you need to have a bunch of face-to-face interactions. See you around!"

9 months ago

what? no, i'm not a vampire. watch i can literally go in the sun (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp) (-1 hp)

2 years ago
Macrophage Defector

Macrophage Defector

Natural killer cells are a type of immune cell that protects the body against not only invading pathogens but also cancer, providing an innate defence against these rogue cells. Some tumours, however, keep natural kill cells at bay and thereby avoid destruction. And recent research in lung tumours reveals this natural killer cell exclusion is achieved with the help of another immune cell – the macrophage. The particular culprit is a type of macrophage covered in a protein called TREM2 – an anti-inflammatory factor. Shown above is a lung tumour (green) packed with TREM2-expressing macrophages (red) that are protecting the cancer from attack. Why these macrophages switch allegiance and side with enemy is unclear, but blocking TREM2 while boosting natural killer cell activity was shown to reduce lung tumour growth in mice suggesting a similar approach might be effective in promoting tumour regression in humans too.

Written by Ruth Williams

Image from work by Matthew D. Park and Ivan Reyes-Torres, and colleagues

Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Image copyright held by the original authors

Research published in Nature Immunology, April 2023

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8 months ago

There are three versions of yourself: the version of you that you see, the version of you that others see, and you as you really are.

1 year ago

Code that includes commented out code negatively impacts performance. Removing the commented out code improves performance. TFW you realize commented out code is being parsed and it's causing effects.


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1 year ago

Your ability to describe the world affects how you think about it. If the language and idioms you know are constrained to a particular window, that window will act as a constraint in shaping not only how you see the world, but also how you experience the world.

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