New Technique Captures The Activity Of An Entire Brain In A Snapshot

Here are 17 jaw-dropping photos of space that show us just how small we really are:

This photo of the moon and Earth taken from the International Space Station.

A dwarf galaxy, about 11 million light-years away from us.

Earth as seen from the moon in 1968.

A cluster of stars, 20,000 light-years away from Earth.

The first flower grown in the International Space Station, photographed by astronaut Scott Kelly.

Saturn, seen through an infared filter.

These visible “loops” on the surface of the sun can reach up to 15 times the diameter of Earth in height.

The Northen Lights just North of Chicago, viewed from the International Space Station.

The Quintuplet Cluster, located 100 light-years from the center of our galaxy.

Pluto and one of its moons, Charon.

The Great Pyramids of Giza, seen from space.

Astronaut Bruce McCandless maneuvering, untethered, above Earth in 1984.

Galaxy NGC 6240, 400 million light-years away from Earth.

Palomar 12, a cluster of stars on the outskirts of the Milky Way.

The remnants of an exploded star.

New York City, seen from the International Space Station.

And the remains of a supernova whose explosion may have been seen almost 2,000 years ago by Chinese astronomers.

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Chaotic behaviour in 50-link pendulum.

First birds made honking sounds more than 66 million years ago

A new fossil discovery has shown that birds developed the unique vocal organ that enables them to sing more than 66 million years ago when dinosaurs were around

Birds developed the unique vocal organ that enables them to sing more than 66 million years ago when dinosaurs walked the Earth, a new fossil discovery has shown.

But the earliest syrinx, an arrangement of vibrating cartilage rings at the base of the windpipe, was still a long way from producing the lilting notes of a song thrush or blackbird.

Scientists believe the extinct duck and goose relative that possessed the organ was only capable of making honking noises.

The bird, Vegavis iaai, lived during the Cretaceous era. Although its fossil bones were unearthed from Vega Island in Antarctica in 1992, it was not until three years ago that experts spotted the syrinx.

All birds living today are descended from a particular family of dinosaurs that developed feathers and the ability to fly.

The new discovery suggests the syrinx is another hallmark of birds that was absent from non-avian dinosaurs…

He’s huge….

Is this the whole thing??? It’s the first time I’ve seen this version.

Ye

Yes, that’s the whole image

Let’s hop this simple solution sticks around (x) | follow @the-future-now

Machine Learning: An In-Depth, Non-Technical Guide

A good introductory text in five parts:

Overview, goals, learning types, and algorithms

Data selection, preparation, and modeling

Model evaluation, validation, complexity, and improvement

Model performance and error analysis

Unsupervised learning, related fields, and machine learning in practice

By  Alex Castrounis - {InnoArchiTech}

Glutamate, an essential food for the brain

Glutamate is an amino acid with very different functions: in the pancreas, it modulates the activity of the pancreatic ß-cells responsible for insulin production, whereas in the brain it is the main excitatory neurotransmitter. In recent years, it has been suspected to play an additional role in the functioning of the brain. By discovering how the brain uses glutamate to produce energy, researchers at the University of Geneva (UNIGE) confirm this hypothesis and highlight unexpected links with the rest of the body. To read in Cell Reports.

Unlike other organs, the brain cannot draw its energy from lipids, an energy resource widely present in the body. The blood-brain barrier, which protects it from the pathogens and toxins circulating in the blood, indeed limits the passage of these lipids. Moreover, while most of the organs in the human body have the ability to store glucose by increasing their mass, the brain, prisoner of the cranial bones, cannot count on these variations in volume. Unable to store its food, it depends on sugar supplied in real-time by the rest of the body. This distribution of energy is controlled by the liver.

Pierre Maechler, professor at the Faculty of Medicine at UNIGE, and his team therefore decided to verify if glutamate was indeed an energy source for the brain. To do so, the researchers analyzed the role of the glutamate dehydrogenase enzyme in the brain. In mutant form, this enzyme, encoded by the Glud1 gene, is responsible for a congenital hyperinsulinism syndrome, a severe disease affecting at the same time the endocrine pancreas, the liver and the brain. Individuals affected by this syndrome suffer from intellectual disability and have a high risk of epilepsy. “We have suppressed the Glud1 gene in the brain of mice. In the absence of glutamate dehydrogenase, we observed that the brain was no longer able to convert glutamate into energy, even though the amino acid was present in the brain,” explains Melis Karaca, first author of this study.

Priority to the brain

Devoid of the energy supplied by cerebral glutamate, the brain sends signals to the liver to requisition a compensatory proportion of glucose, at the expense of the rest of the body. This is why the transgenic mice also showed a growth deficit and muscle atrophy. “This clearly shows how the brain works in a just-in-time manner and that each percent of energy resources is essential for its proper functioning,” highlights Professor Pierre Maechler. “If a part of this energy disappears, the brain serves itself first and the rest of the body suffers. The liver must then make more glucose by drawing upon muscle protein, resulting in loss of muscle mass. Knowing that the brain uses glutamate as an energy resource allows us to reflect on other ways to overcome a potential shortfall. ”

Scientists also suspect a correlation between the Glud1 gene and some neurodevelopmental disorders, particularly epilepsy and schizophrenia. They are currently pursuing their research by introducing in mice the same Glud1 mutation detected in epileptic patients. At the same time, another group is working with schizophrenic patients to assess the way their brain uses glutamate.

A puzzling expected value

Pick a (uniformly) random real number from the unit interval [0,1] and repeat this until the sum of all chosen numbers exceeds 1. What is the expected number of real values you will pick?

The quite surprising answer is Eulers constant, e ≈ 2.71828.

A demonstration can be found on Wolfram MathWorld.

Better late than never!

This week’s entry: Hot Jupiters

http://www.space.com/32011-extremely-hot-and-fast-planets-seem-to-defy-logic.html

https://astrobites.org/2015/03/04/hot-jupiters-are-very-bad-neighbors/