Neisseria Gonorrhoeae

Colon: pseudomembranous colitis due to Clostridium difficile (pseudomembranous inflammation) Note the gray-yellow pseudomembrane covering the entire mucosal surface. Damage is due to a toxin produced by C. difficile. Similar to diphtheria, the toxin produces necrosis of the mucosa and submucosa without actual invasion by the bacteria. A toxin assay of stool is the best method for diagnosing the disease. Ampicillin is the MC drug causing pseudomembranous colitis and does so by destroying colonic bacteria that normally keep C. difficile in check.

Some general resources:

Chemistry Glossary

Chemistry Exam Survival Guide

Toolbox – interactive graphing, tables, and calculators

Make virtual chemistry models

Interactive periodic table

Another site for making virtual chemistry models

Virtual labs – covers stoichiometry, thermochemistry, eq1uilibrium, acid base chemistry, solubility, oxidation/reduction and electrochemistry, analytical chemistry/lab techniques

Concept tests

Chemistry Science Fair Project Ideas

OChem Reaction Bank

Interactive chem simulations

Chemical calculations

The Chem Blog

Molecule of the day

Free chemistry drawing software

Laboratory Safety - Laboratory safety for the chemistry classroom

Periodic Table of Videos - Brady Haran

On this day in chemistry… - a history of chemistry

The faces of chemistry

Experimentation hub -  explore and enjoy our experiments to increase engagement in scientific investigation, develop new skills and enhance your knowledge.

Understanding journals - including reading articles, referencing, and example articles.

Resources for specific topics:

Stochiometry – the mole, molarity and density, reaction stoichiometry and limiting reagents, empirical formula and mixtures, gravimetric analysis

Themochemistry – energy and enthalpy, entropy

Kinetics – phenomenological and mechanistic kinetics

Equilibrium – LeChatlier’s principle, progress of reaction, equilibrium calculations, common ion effect

Acid base chemistry – strong acid and bases, weak acids and bases, buffer solutions, acid/base titrations

Solubility – solubility product, solubility and PH, common ion effect

Oxidation/Reduction and Electrochemistry – standard reduction potentials, galvanic cells

Analytical chemistry/ Lab techniques – reaction stoichiometry and limiting reagents, acid/base titrations, redox titrations, gravimetric analysis, UC/Vis spectroscopy

Physical chemistry – quantum mechanics, spectroscopy

Properties of solutions – intermolecular forces, colligative properties

Textbooks:

Chemistry Virtual Textbooks, Stephen Lower

Organic Chemistry, Tim Soderberg

Organic Chemistry I, George Mhehe

Environmental Chemistry, Dejene Tessema

Virtual Organic Chemistry

Industrial Chemistry, Helen Njenga

Inorganic Chemistry, Chrispin Kowenje

Physical Chemistry I, Onesmus Munyaki

General Chemistry, Principles, Patterns and Applications

Chemistry Books - a variety of chemistry textbooks

Chemistry Tutorials/Guides:

Atoms, Molecules, and Ions

Chemical reactions and stoichiometry

Electronic structure of atoms

Periodic table

Chemical bonds

Gases and kinetic molecular theory

State of matter and intermolecular forces

Chemical equilibrium

Acids and bases

Acid base equilibria and solubility equilibria

Thermodynamics

Redox reactions and electrochemistry

Kinetics

Nuclear chemistry

Organic Chemistry Tutorials/Guidelines:

Structure and bonding

Dot structures

Hybridization

Bond-line structures

Electronegativity

Resonance and acid base chemistry

Counting electrons

Resonance structures

Organic acid-base chemistry

Alkanes, cycloalkanes and functional groups

Naming alkanes

Naming alkanes, cycloalkanes, and bicyclic compounds

Conformations of alkanes

Conformations of cycloalkanes

Functional groups

Stereochemistry

Chirality

Enantiomers

Stereoisomeric relationships

Subsituation and elimination reactions

Free radical reaction

Sn1 vs Sn2

Nucleophilicity and basicity

Elimination reactions

Sn1/Sn2/E1/E2

Sn1 and Sn2

Alkenes and alkynes

Naming alkenes

Alkene reactions

Alkene nomenclature

Alkene reactions

Naming and preparing alkynes

Alkyne reactions

Alcohols, ethers, epoxides, sulphides

Alcohol nomenclature and properties

Synthesis of alcohols

Reactions of alcohols

Nomenclature and properties of ethers

Synthesis and cleavage of ethers

Nomenclature and preparation of epoxides

Conjugation, Diels-Alder, and MO theory

Addition reactions of conjugated dienes

Diels-Alder reaction

Molecular orbital theory

Aromatic compounds

Naming benzene derivatives

Reactions of benzene

Aromatic stability

Electrophilic aromatic substitution

Directing effects

Other reactions and synthesis

Aldehydes and ketones

Introduction to aldehydes and ketones

Reactions of aldehydes and ketones

Carboxylic acids and derivatives

Naming carboxylic acids

Formation of carboxylic acid derivatives

Nomenclature and reactions of carboxylic acids

Nomenclature and reactions of carboxylic acid derivatives

Alpha carbon chemistry

Formation of enolate anions

Aldol condensations

Amines

Naming amines

Spectroscopy

Infrared Spectroscopy

UV/Vis Spectroscopy

proton NMR

Careers:

A future in Chemistry

What can I do with my chemistry degree?

Chemistry Careers - American Chemical Society

What to do with a degree in chemistry - The Guardian

A sample of notes from Medical Virology // I keep the margins empty so that I have space to add in relevant additional material from extra reading

[17 Dec 2017] (i thought i’d posted but it’s not appearing? ):) so sorry for the lack of original posts all these months! school has been so tough & i’ve just completed my mid-sem assessments & it’s finally my break! can’t wait to unwind and catch up on my sleep ;-;

CYSTIC FRIBROSIS

G511D mutation: missense mutation, Glycine replaced by Aspartate.

Only 5% of pts with CF have this mutation.

Defective channel opening or gating.

IVACAFTOR: new drug, acts directly in the CFTR channel, opens it up. First drug that afects the ethiology :)

Trade name: Kalydeco

Staphylococcus epidermidis is a coagulase negative, Gram-positive coccus. The organism uses sophisticated regulatory networks to adapt its metabolism to suit varying environmental conditions. S. epidermidis relies on biofilm formation to protect cells from the host immune system and other anti-microbial molecules.

Amazing web site!

It’s Medical Mnemonics Monday!

Renal Papillary Necrosis is a form of nephropathy characterized by coagulative necrosis of the renal medullary pyramids and papillae.  

Causes of Papillary Necrosis can be remembered by the mnemonic “POSTCARDS”.

P yelonephritis

O bstruction of the urogenital tract

S ickle cell disease

T uberculosis

Chronic liver disease,

A nalgesia /A lcohol abuse,

R enal transplant rejection

D iabetes mellitus

S ystemic vasculitis

Check out the list of the previous Medical Mnemonics here.

Mycobaterium tuberculosis PATHOGENESIS

Facultative intracellular

Sulfatides: inhibit PHAGOLYSOSOME FORMATION allowing intracellular survival.

Cord Factor (serpentine growth in vitro): disrupts mithochondrial respiration and oxidative phosphorilation and inhibits leukocyte migration.

Tuberculin + Mycolic Acid: type IV hypersensitivity (delayed hs), Cellular Mediated Immunity (CMI)

….and that is how viruses go about their non-lives!!

my biology professor at the end of a lecture about viruses, presumably, i wouldn’t know, i wasn’t paying attention, i’m using context clues here (via scienceprofessorquotes)