White Blood Cells (Leukocytes)
Neutrophils, eosinophils and basophils = granulocytes (polymorphonuclear leukocytes)
Monocytes & lymphocyes = mononuclear
Most numerous (~60% of WBC)
Nucleus divided into lobes
Cytoplasm contains small granules
Stains pink with Romanowsky dyes
Lifespan of 6-10hrs
Exit into tissues - non-specific defence against bacteria and fungi
1% of circulating leukocytes
Large cytoplasmic granules - stain strongly with acidic dye eosin
Nucleus is bilobed
Circulate for 4-5hrs
Exit to tissues –>
Defence against parasites
Dampen allergic response
Tissue eosinophils are also capable of responding to bacterial and fungal infection in a similar way to neutrophils.
Least numerous (<1%)
Large granules stain strongly with basic dye methylene blue
Involved in anaphylactic hypersensitivity and inflammatory reactions
5% of circulating leukocytes
Large cell
Kidney/clefted shaped nucleus
Scattering of delicate azurophilic granules
Circulate for 10hrs
Mature into phagocytic tissue macrophages
Responsible for the removal of aged RBCs and other debris
Process and present antigens to T-lymphocytes
(Macrophages are formed in response to an infection or accumulating damaged or dead cells. Large, specialized cells that recognize, engulf and destroy target cells.)
Second most common leukocyte (33%)
Much less cytoplasm - nucleus almost fills cell
Variable lifespan
Receptors on surface recognise foreign substances
Several types of lymphocyte - click here
Gram+, anaerobic, non-spore forming, branching rod
Endogenous transmission (dental crevices -bad higiene, dental trauma- ; female genital tract -IUD-)
Dx: branching rods in “sulfur granules”; colonies resemble a molar tooth.
Not painful but very invasive penetrating tissues, including bone.
Draining abscess (sinus tracts) CULTURE THAT PUS
Disease: ACTINOMYCOSIS in low O2 tissues
Cervicofacil: “Lumpy jaw”, mycetoma on jaw line
Pelvic: from IUD
CNS: solitary abscess
Abdominal: qx, trauma
Thoracic: aspiration
(Day 4/100 days of productivity) - Haemophilus Influenzae card!
Today was mostly spent working on research, textbooks, but and making flashcards like this for microbiology!
Most Common facts about infectious diseases
1. Most common cause of septic arthritis in a person less than 40 years old = Gonococcus 2. Most common cause of osteomyelitis in general population = S. aureus 3. Most common cause of osteomyelitis in Sickle Cell patients = Salmonella 4. Most common cause of osteomyelitis due to nail-puncture wounds = Pseudomonas (V.Imp!) 5. Most common parasitic infection of the brain = Neurocysticercosis 6. Most common cause of Encephalitis in USA = Herpes Simplex Virus (HSV) 7. Most common cause of dysentry in the USA = C. jejuni (undercooked poultry) 8. Second most cause of dysentry in the USA = Shigella (daycare centers) 9. Most common cause of pneumonia in nursing home residents = S. pneumoniae 10. Most common cause of malignant otitis externa = P. aeruginosa 11. Most common risk for contracting HIV in USA= Intravenous Drug Use 12. Most common presenting Manifestation of AIDs = P. carinii pneumonia 13. Most common cause of Menigitis in adolescents = N. Gonorhhaea 14. Most common cause of Meningitis in the USA = Streptococcus pneumoniae 15. Most common Neurological Manifestation of Lyme Disease = Facial Nerve palsy! 16. Most common Cardiac manifestation of Lyme Disease = AV Heart Block 17. Most Common viral STD in the USA = HPV ! 18. Most Common Complication of Mumps in Pre-pubertal Children = Encephalitis 19. Most Common Complication of Mumps in Pubertal and Post-Pubertal Adults (and Males) = Orchitis
Guys, I love ID. I really hope I get to do an ID rotation on Medicine. If you remember, I once posted the mnemonic I swear by for viruses. Well here is the bacteria counterpart. Also your micro mantra should be: sketchy is life. Love Andrew like I do (this part’s not the mantra, I just love Andrew).
Let me know if you have any questions or need clarification. This is a perfect example of a “not aesthetically pleasing tumblr study post” because sometimes your handwriting sucks and you aint got that kinda time in my life for pretty arrows and banners and I just wanna finish this shit so I can leave the library when will Step 1 even be over why is this my liiiiiife
Organophosphate poisoning VS Atropine poisoning
Endospore
Different anatomy notes form this semester Supplies used (not all at once, I mix and match): Faber-Castell Coloured Pencils (48 Pack) - https://amzn.to/2Kd1mUy Staedtler Triplus Fineliners - http://amzn.to/2pghonI Stabilo Point 88 Fineliner - https://amzn.to/2qU8fC9 Sharpie Pens - https://amzn.to/2HTRmP2 Uni Pin 0.1 Fineliner - https://amzn.to/2HmXp1z Crayola Supertips - https://amzn.to/2HVW1jr Bic Ballpoint Pen - https://amzn.to/2HmCjk0 Stabilo Swing Cool Highlighters - https://amzn.to/2HKxPTu