One Of The Most Dangerous Pictures Ever Taken - Elephant’s Foot, Chernobyl. This Is A Photo Of A Now

Using the Power of Space to Fight Cancer

From cancer research to DNA sequencing, the International Space Space is proving to be an ideal platform for medical research. But new techniques in fighting cancer are not confined to research on the space station. Increasingly, artificial intelligence is helping to “read” large datasets. And for the past 15 years, these big data techniques pioneered by our Jet Propulsion Laboratory have been revolutionizing biomedical research.

Microgravity Research on Space Station

On Earth, scientists have devised several laboratory methods to mimic normal cellular behavior, but none of them work exactly the way the body does. Beginning more than 40 years ago aboard Skylab and continuing today aboard the space station, we and our partners have conducted research in the microgravity of space.  In this environment, in vitro cells arrange themselves into three-dimensional groupings, or aggregates. These aggregates more closely resemble what actually occurs in the human body. Cells in microgravity also tend to clump together more easily, and they experience reduced fluid shear stress – a type of turbulence that can affect their behavior. The development of 3D structure and enhanced cell differentiation seen in microgravity may help scientists study cell behavior and cancer development in models that behave more like tissues in the human body.

In addition, using the distinctive microgravity environment aboard the station, researchers are making further advancements in cancer therapy. The process of microencapsulation was investigated aboard the space station in an effort to improve the Earth-based technology. Microencapsulation is a technique that creates tiny, liquid-filled, biodegradable micro-balloons that can serve as delivery systems for various compounds, including specific combinations of concentrated anti-tumor drugs. For decades, scientists and clinicians have looked for the best ways to deliver these micro-balloons, or microcapsules, directly to specific treatment sites within a cancer patient, a process that has the potential to revolutionize cancer treatment.

A team of scientists at Johnson Space Center used the station as a tool to advance an Earth-based microencapsulation system, known as the Microencapsulation Electrostatic Processing System-II (MEPS-II), as a way to make more effective microcapsules. The team leveraged fluid behavior in microgravity to develop a new technique for making these microcapsules that would be more effective on Earth. In space, microgravity brought together two liquids incapable of mixing on Earth (80 percent water and 20 percent oil) in such a way that spontaneously caused liquid-filled microcapsules to form as spherical, tiny, liquid-filled bubbles surrounded by a thin, semipermeable, outer membrane. After studying these microcapsules on Earth, the team was able to develop a system to make more of the space-like microcapsules on Earth and are now performing activities leading to FDA approval for use in cancer treatment.  

In addition, the ISS National Laboratory managed by the Center for the Advancement of Science in Space (CASIS) has also sponsored cancer-related investigations.  An example of that is an investigation conducted by the commercial company Eli Lilly that seeks to crystallize a human membrane protein involved in several types of cancer together with a compound that could serve as a drug to treat those cancers. 

“So many things change in 3-D, it’s mind-blowing – when you look at the function of the cell, how they present their proteins, how they activate genes, how they interact with other cells,” said Jeanne Becker, Ph.D., a cell biologist at Nano3D Biosciences in Houston and principal investigator for a study called Cellular Biotechnology Operations Support Systems: Evaluation of Ovarian Tumor Cell Growth and Gene Expression, also known as the CBOSS-1-Ovarian study. “The variable that you are most looking at here is gravity, and you can’t really take away gravity on Earth. You have to go where gravity is reduced." 

Crunching Big Data Using Space Knowledge

Our Jet Propulsion Laboratory often deals with measurements from a variety of sensors – say, cameras and mass spectrometers that are on our spacecraft. Both can be used to study a star, planet or similar target object. But it takes special software to recognize that readings from very different instruments relate to one another.

There’s a similar problem in cancer research, where readings from different biomedical tests or instruments require correlation with one another. For that to happen, data have to be standardized, and algorithms must be “taught” to know what they’re looking for.

Because space exploration and cancer research share a similar challenge in that they both must analyze large datasets to find meaning, JPL and the National Cancer Institute renewed their research partnership to continue developing methods in data science that originated in space exploration and are now supporting new cancer discoveries.

JPL’s methods are leading to the development of a single, searchable network of cancer data that researcher can work into techniques for the early diagnosis of cancer or cancer risk. In the time they’ve worked together, the two organizations’ efforts have led to the discovery of six new Food and Drug Administration-approved cancer biomarkers. These agency-approved biomarkers have been used in more than 1 million patient diagnostic tests worldwide.

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Happy Ada Lovelace day - here's why we should all remember her

Today is Ada Lovelace Day. Who's that? Just the first computer programmer. Ever.

Lovelace’s friend Charles Babbage designed a concept for a machine he called the “Analytical Engine” – essentially a mechanical computer that would have relied on punch cards to run programs. He recruited Lovelace to translate some notes from one of his lectures, but while Lovelace was translating she added to the notes herself.

The notes grew to three times their original length, as Lovelace described what many call the first computer program. Because of funding issues, the machine was not built during her and Babbage’s lifetimes.

But Lovelace’s published article on the Analytical Engine later became a source of inspiration for Alan Turing’s work to build the first modern computers in the 1940s.

Women are sometimes considered outsiders in the science and technology fields, but Lovelace and many of the female computer programmers who followed her are proof that this paucity is a function of society, not capability. We forget or never learn about the female “computers” who programmed early mechanical machines in World War II, or that the women’s magazine Cosmopolitan once ran articles suggesting that women were perfectly suited for programming.

If the lack of acknowledgement of women’s contributions to science, technology, engineering, and mathematics (STEM) fields grinds your gears, then Ada Lovelace should be one of the first names you go to right that wrong.

Further reading:

Wikipedia profile

10 Things You May Not Know About Ada Lovelace

What if there were more women in tech?

Why we ALL need to celebrate Ada Lovelace Day

Superhenge?

Last year, an international team of scientists mapping the underground landscape surrounding Stonehenge announced that they had located a massive stone monument that dwarfed its ancient neighbor. When archaeologists started excavating “Superhenge” earlier this month, however, they found something completely different.

Keep reading

The Ghetto of Venice

2016: This Year at NASA!

As 2016 comes to a close and prospects of the new year loom before us, we take a moment to look back at what we’ve accomplished and how it will set us ahead in the year to come.

2016 marked record-breaking progress in our exploration activities. We advanced the capabilities needed to travel farther into the solar system while increasing observations of our home and the universe, learning more about how to continuously live and work in space and, or course, inspiring the next generation of leaders to take up our journey to Mars and make their own discoveries.

Here are a few of the top NASA stories of 2016…

International Space Station

One Year Mission…completed!

NASA astronaut Scott Kelly and Russian cosmonaut Mikhail Kornienko returned to Earth after spending a year in space. Testing the limits of human research, findings from their One Year Mission will help send humans farther into space than ever before.

Commercial Resupply

Commercial partners Orbital ATK and SpaceX delivered tons (yes literally tons) of cargo to the International Space Station. This cargo supported hundreds of science experiments and technology demonstrations crucial to our journey to Mars.

Mars

Expandable Habitats

The Bigelow Expandable Activity Module (BEAM) was one of the technology demonstrations delivered to the space station in April. Expandable habitats greatly decrease the amount of transport volume for future space missions.

Booster Test Firing

In June, a booster for our Space Launch System (SLS) rocket successfully fired up. It will be used on the first un-crewed test flight of SLS with the Orion spacecraft in 2018. Eventually, this rocket and capsule will carry humans into deep space and one day…Mars!

InSight

This year we updated the milestones for our InSight mission with a new target launch window beginning in May 2018. This mission will place a fixed science outpost on Mars to study its deep interior. Findings and research from this project will address one of the most fundamental questions we have about the planetary and solar system science…how in the world did these rocky planets form?

Solar System and Beyond

Juno

On July 4, our Juno spacecraft arrived at Jupiter. This mission is working to improve our understanding of the solar system’s beginnings by revealing the origin and evolution of Jupiter.

OSIRIS-REx

In September, we launched our OSIRIS-REx spacecraft…which is America’s first-ever asteroid sample return mission. This spacecraft will travel to a near-Earth asteroid, called Bennu, where it will collect a sample to bring back to Earth for study.

James Webb Space Telescope

In February, the final primary mirror segment of our James Webb Space Telescope was installed. This will be the world’s most powerful space telescope ever, and is scheduled to launch in 2018. Webb will look back in time, studying the very first galaxies ever formed.

Kepler

In May, our Kepler mission verified the discovery of 1,284 new planets. Kepler is the first NASA mission to find potentially habitably Earth-sized planets.

Earth Right Now

Earth Expeditions

Our efforts to improve life on Earth included an announcement in March of a collection of Earth Science field campaigns to study how our planet is changing. These Earth Expeditions sent scientists to places like the edge of the Greenland ice sheet to the coral reefs of the South Pacific to delve into challenging questions about how our planet is changing…and what impacts humans are having on it.

Small Satellites

In November, we announced plans to launch six next-generation Earth-observing small satellite missions. One uses GPS signals to measure wind in hurricanes and tropical systems in greater detail than ever before.

Aeronautics Research

Our efforts in 2016 to make air travel cleaner, safer and quieter included new technology to improve safety and efficiency of aircraft arrivals, departures and service operations.

X-Plane

In June, we highlighted our first designation of an experimental airplane, or X-plane, in a decade. It will test new electric propulsion technology.

Drone Technolgy

In October, we evaluated a system being developed for the Federal Aviation Administration to safely manage drone air traffic.

Technology

Electric Propulsion

We selected Aerojet Rocketdyne to develop and advanced electric propulsion system to enable deep space travel to an asteroid and Mars.

Spinoffs

Our technology transfer program continued to share the agency’s technology with industry, academia and other government agencies at an unprecedented rate.

Centennial Challenges

Our Centennial Challenges program conducted four competition events in 2016 to spark innovation and enable solutions in important technology focus areas.

Watch the full video recap of ‘This Year @NASA’ here:

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

James Shields (1878 - 1920) is the only person to serve in the US Senate for 3 different states – Illinois, Minnesota, and Missouri.

Getting to Mars: What It’ll Take

Join us as we take a closer look at the next steps in our journey to the Red Planet:

The journey to Mars crosses three thresholds, each with increasing challenges as humans move farther from Earth. We’re managing these challenges by developing and demonstrating capabilities in incremental steps:

Earth Reliant

Earth Reliant exploration is focused on research aboard the International Space Station. From this world-class microgravity laboratory, we are testing technologies and advancing human health and performance research that will enable deep space, long duration missions.

On the space station, we are advancing human health and behavioral research for Mars-class missions. We are pushing the state-of-the-art life support systems, printing 3-D parts and analyzing material handling techniques.

Proving Ground

In the Proving Ground, we will learn to conduct complex operations in a deep space environment that allows crews to return to Earth in a matter of days. Primarily operating in cislunar space (the volume of space around the moon). We will advance and validate the capabilities required for humans to live and work at distances much farther away from our home planet…such as at Mars.

Earth Independent

Earth Independent activities build on what we learn on the space station and in deep space to enable human missions to the Mars vicinity, possibly to low-Mars orbit or one of the Martian moons, and eventually the Martian surface. Future Mars missions will represent a collaborative effort between us and our partners.

Did you know….that through our robotic missions, we have already been on and around Mars for 40 years! Taking nearly every opportunity to send orbiters, landers and rovers with increasingly complex experiments and sensing systems. These orbiters and rovers have returned vital data about the Martian environment, helping us understand what challenges we may face and resources we may encounter.

Through the Asteroid Redirect Mission (ARM), we will demonstrate an advanced solar electric propulsion capability that will be a critical component of our journey to Mars. ARM will also provide an unprecedented opportunity for us to validate new spacewalk and sample handling techniques as astronauts investigate several tons of an asteroid boulder.

Living and working in space require accepting risks – and the journey to Mars is worth the risks. A new and powerful space transportation system is key to the journey, but we will also need to learn new ways of operating in space.

We Need You!

In the future, Mars will need all kinds of explorers, farmers, surveyors, teachers…but most of all YOU! As we overcome the challenges associated with traveling to deep space, we will still need the next generation of explorers to join us on this journey. Come with us on the journey to Mars as we explore with robots and send humans there one day.

Join us as we go behind-the-scenes:

We’re offering a behind-the-scenes look Thursday, Aug. 18 at our journey to Mars. Join us for the following events:

Journey to Mars Televised Event at 9:30 a.m. EDT Join in as we host a conversation about the numerous efforts enabling exploration of the Red Planet. Use #askNASA to ask your questions! Tune in HERE.

Facebook Live at 1:30 p.m. EDT Join in as we showcase the work and exhibits at our Michoud Assembly Facility. Participate HERE.

Hot Fire Test of an RS-25 Engine at 6 p.m. EDT The 7.5-minute test is part of a series of tests designed to put the upgraded former space shuttle engines through the rigorous temperature and pressure conditions they will experience during a launch. Watch HERE.  

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

Vote down ballot - the presidency isn't the only office of importance!

Time for another political essay. If you’re not an American citizen or able to vote in this upcoming election, my apologies.

I make no secret that I fucking despise Donald Trump. I actually like Hillary Clinton, which seems to be a weird rarity considering the amount of good work she’s done and the fact that all of the bad press about her is the result of the Republicans trying (and failing) to tear her and her husband down for thirty years.

Trump is now trailing far behind Clinton, which I consider a cause for celebration. But it is NOT a cause for complacency.

The biggest landslide election in US history was the election of Warren G. Harding in 1920, when Harding won with about 60% of the vote to his opponent’s 34.2%.

Some polls are reporting Trump with as little as 35% of the popular vote right now.

If turnout is large enough and loud enough, we can make Donald Trump the least supported major candidate in US history. Since the recording of him bragging about sexual assault came out, he has turned to dragging the whole election into the mud by striking back at Bill Clinton’s affairs; the usual goal of that kind of tactic is to drive down voter turnout. Trump’s band of Redcaps is pretty much guaranteed to vote, so they figure if they reduce turnout enough, they’ll win.

I want their plan to fail. I want their plan to fail so fucking spectacularly that NO ONE will dare to run for President on a platform of thinly-veiled fascism again.

The Republicans thought the House of Representatives was safe this year. In 2010, they gerrymandered the shit out of district lines to keep the House safe for them for at least ten years. But there’s a problem with gerrymandering: if the demographics shift unexpectedly between censuses, then suddenly a lot of districts wind up flipping against the party that the gerrymandering was meant to support. And Donald Trump is driving away the Republicans’ most secure core of voters, the evangelicals. And as I’ve said before: Congress is MORE important than the presidency.

If turnout is strong enough, and if people vote down ballot, the possibility exists for a massive upset. A Democratic presidency, a Democratic House, a Democratic Senate. They’re within our grasp. All you need to do, voters, is show up.

Motherfuckers don’t want you to vote. Young people, people of color, women, LGBTQ+ folks–they want you to be scared away, or to be convinced that voting doesn’t matter. They want your voice silenced. Don’t give the fuckers the satisfaction of letting it happen.

GO VOTE. VOTE DOWN-BALLOT. MAKE TRUMP THE BIGGEST LOSER IN US HISTORY.

IF YOU CAN’T BE BOTHERED TO VOTE OUT OF CONVICTION, THEN DO IT OUT OF SPITE.

Flat House + Atelier So-So. 鶴川の家 - Tsurukawa House.  Kanagawa. Japan. photos: Flat House