Rabies Viruses Reveal Wiring In Transparent Brains

Rabies Viruses Reveal Wiring In Transparent Brains

Rabies Viruses Reveal Wiring in Transparent Brains

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants. Coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to the host neural network.

The research is in Nature Communications. (full open access)

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More Posts from Smparticle2 and Others

8 years ago
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official
A Rare Screentest Of Vivien Leigh And Clark Gable, Just After Vivien Had Been Announced As The Official

A rare screentest of Vivien Leigh and Clark Gable, just after Vivien had been announced as the official actress portraying Scarlett O’hara. A Selznick employee remembers, “Gable knew this was a woman’s picture and treated her with the utmost respect.”

8 years ago
Austria

Austria

Taken By SusanK31

7 years ago

Behind a TED-Ed Lesson: Animation + Inspiration

To celebrate George Seurat’s birthday today, we thought we’d do a deep dive behind the scenes of one of our animated lessons, How do schools of fish swim in harmony?, which is about the concept of ‘emergence’ and whose animated style just so happens to have been largely influenced by the paintings of George Seurat and his contemporaries.

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Emergence refers to the spontaneous creation of sophisticated behaviors and functions from large groups of simple elements, and can be used to explain the movements of ants, fish, and birds, as well as how the tiny cells in your brain give rise to the complex thoughts, memories, and consciousness that are you.

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A Sunday Afternoon on the Island of La Grande Jatte, George Seurat (1884–86)

It’s kind of like a pointillist painting. When you zoom in real close, it’s just a collection of chaotic brush strokes. But take a few steps back, and you’ll see that all of those brush strokes are working together to illustrate a complex and detailed scene.

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Pointillism stems from Impressionism, and depending on the artist’s technique, the size of the brush strokes vary, but are always visible. For example, Vincent van Gogh’s The Starry Night uses larger brush strokes in the night sky. Both the above and below concept designs show the animator of this lesson testing out how different brushstrokes interact to create depth within a scene. She decided that the swirling waters would make sense as large brushstrokes, which also offered contrast to allow the small fish to stand out.

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George Seurat also employed a technique called ‘divisionism’, sometimes known as ‘chromoluminarism’, in which colors were separated into individual dots or patches which interacted optically. So, rather than relying on mixing colors, painters like Seurat and Paul Signac juxtaposed contrasting colors to allow for optical mixing - which in theory would produce more vibrant and pure colors than the traditional process of mixing pigments.

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Circus Sideshow (Parade de Cirque), George Seurat (1887–88)

While designing this TED-Ed lesson, George Seurat and Paul Signac’s paintings provided inspiration not just for the brushstroke technique, but also for the color palette.

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This GIF of the brain and it’s neural connections draws many of its colors from Seurat’s circus series palette, while the brighter colors - such as the ones used in the title GIF above - are drawn from the more vibrant colors commonly used by Paul Signac, like in the painting below.

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Notre-Dame-de-la-Garde (La Bonne-Mère), Marseilles, Paul Signac (1905-06)

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Animating this lesson was an opportunity to renew a sense of wonder in our ever complex universe, whether studying it up close or from afar. We hope that watching it might do the same for you!

From the TED-Ed Lesson How do schools of fish swim in harmony? - Nathan S. Jacobs

Animation by TED-Ed // Lisa LaBracio


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7 years ago

Webb 101: 10 Facts about the James Webb Space Telescope

Did you know…?

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1. Our upcoming James Webb Space Telescope will act like a powerful time machine – because it will capture light that’s been traveling across space for as long as 13.5 billion years, when the first stars and galaxies were formed out of the darkness of the early universe.

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2. Webb will be able to see infrared light. This is light that is just outside the visible spectrum, and just outside of what we can see with our human eyes.

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3. Webb’s unprecedented sensitivity to infrared light will help astronomers to compare the faintest, earliest galaxies to today’s grand spirals and ellipticals, helping us to understand how galaxies assemble over billions of years.

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Hubble’s infrared look at the Horsehead Nebula. Credit: NASA/ESA/Hubble Heritage Team

4. Webb will be able to see right through and into massive clouds of dust that are opaque to visible-light observatories like the Hubble Space Telescope. Inside those clouds are where stars and planetary systems are born.

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5. In addition to seeing things inside our own solar system, Webb will tell us more about the atmospheres of planets orbiting other stars, and perhaps even find the building blocks of life elsewhere in the universe.

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Credit: Northrop Grumman

6. Webb will orbit the Sun a million miles away from Earth, at the place called the second Lagrange point. (L2 is four times further away than the moon!)

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7. To preserve Webb’s heat sensitive vision, it has a ‘sunshield’ that’s the size of a tennis court; it gives the telescope the equivalent of SPF protection of 1 million! The sunshield also reduces the temperature between the hot and cold side of the spacecraft by almost 600 degrees Fahrenheit.

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8.  Webb’s 18-segment primary mirror is over 6 times bigger in area than Hubble’s and will be ~100x more powerful. (How big is it? 6.5 meters in diameter.)

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9.  Webb’s 18 primary mirror segments can each be individually adjusted to work as one massive mirror. They’re covered with a golf ball’s worth of gold, which optimizes them for reflecting infrared light (the coating is so thin that a human hair is 1,000 times thicker!).

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10. Webb will be so sensitive, it could detect the heat signature of a bumblebee at the distance of the moon, and can see details the size of a US penny at the distance of about 40 km.

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BONUS!  Over 1,200 scientists, engineers and technicians from 14 countries (and more than 27 U.S. states) have taken part in designing and building Webb. The entire project is a joint mission between NASA and the European and Canadian Space Agencies. The telescope part of the observatory was assembled in the world’s largest cleanroom at our Goddard Space Flight Center in Maryland.

Webb is currently being tested at our Johnson Space Flight Center in Houston, TX.

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Afterwards, the telescope will travel to Northrop Grumman to be mated with the spacecraft and undergo final testing. Once complete, Webb will be packed up and be transported via boat to its launch site in French Guiana, where a European Space Agency Ariane 5 rocket will take it into space.

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Learn more about the James Webb Space Telescope HERE, or follow the mission on Facebook, Twitter and Instagram.

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

7 years ago

Spacewalk Recap Told in GIFs

Friday, Oct. 20, NASA astronauts Randy Bresnik and Joe Acaba ventured outside the International Space Station for a 6 hour and 49 minute spacewalk. Just like you make improvements to your home on Earth, astronauts living in space periodically go outside the space station to make updates on their orbiting home.

During this spacewalk, they did a lot! Here’s a recap of their day told in GIFs…

All spacewalks begin inside the space station. Astronauts Paolo Nespoli and Mark Vande Hei helped each spacewalker put on their suit, known as an Extravehicular Mobility Unit (EMU).

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They then enter an airlock and regulate the pressure so that they can enter the vacuum of space safely. If they did not regulate the pressure safely, the astronauts could experience something referred to as “the bends” – similar to scuba divers.

Once the two astronauts exited the airlock and were outside the space station, they went to their respective work stations.

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Bresnik replaced a failed fuse on the end of the Dextre robotic arm extension, which helps capture visiting vehicles.

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During that time, Acaba set up a portable foot restraint to help him get in the right position to install a new camera.

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While he was getting set up, he realized that there was unexpected wearing on one of his safety tethers. Astronauts have multiple safety mechanisms for spacewalking, including a “jet pack” on their spacesuit. That way, in the unlikely instance they become untethered from the station, the are able to propel back to safety.

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Bresnik was a great teammate and brought Acaba a spare safety tether to use.

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Once Acaba secured himself in the foot restraint that was attached to the end of the station’s robotic arm, he was maneuvered into place to install a new HD camera. Who was moving the arm? Astronauts inside the station were carefully moving it into place!

And, ta da! Below you can see one of the first views from the new enhanced HD camera…(sorry, not a GIF).

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After Acaba installed the new HD camera, he repaired the camera system on the end of the robotic arm’s hand. This ensures that the hand can see the vehicles that it’s capturing.

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Bresnik, completed all of his planned tasks and moved on to a few “get ahead” tasks. He first started removing extra thermal insulation straps around some spare pumps. This will allow easier access to these spare parts if and when they’re needed in the future.

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He then worked to install a new handle on the outside of space station. That’s a space drill in the above GIF. 

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After Acaba finished working on the robotic arm’s camera, he began greasing bearings on the new latching end effector (the arm’s “hand”), which was just installed on Oct. 5.

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The duo completed all planned spacewalk tasks, cleaned up their work stations and headed back to the station’s airlock. 

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Once safely inside the airlock and pressure was restored to the proper levels, the duo was greeted by the crew onboard. 

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They took images of their spacesuits to document any possible tears, rips or stains, and took them off. 

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Coverage ended at 2:36 p.m. EDT after 6 hours and 49 minutes. We hope the pair was able to grab some dinner and take a break!

You can watch the entire spacewalk HERE, or follow @Space_Station on Twitter and Instagram for regular updates on the orbiting laboratory. 

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

8 years ago
Yerres, Path Through The Old Growth Woods In The Park Via Gustave Caillebotte

Yerres, Path Through the Old Growth Woods in the Park via Gustave Caillebotte

Size: 43x31 cm Medium: oil on canvas

8 years ago
“I Travel Around The World, Eat A Lot Of Shit, And Basically Do Whatever The Fuck I Want.”  Read

“I travel around the world, eat a lot of shit, and basically do whatever the fuck I want.”  Read our complete Profile of Anthony Bourdain here. 

7 years ago
How Do You Build A Metal Nanoparticle?

How do you build a metal nanoparticle?

Novel theory explains how metal nanoparticles form

Although scientists have for decades been able to synthesize nanoparticles in the lab, the process is mostly trial and error, and how the formation actually takes place is obscure. However, a study recently published in Nature Communications by chemical engineers at the University of Pittsburgh’s Swanson School of Engineering explains how metal nanoparticles form.

“Thermodynamic Stability of Ligand-Protected Metal Nanoclusters” (DOI: 10.1038/ncomms15988) was co-authored by Giannis Mpourmpakis, assistant professor of chemical and petroleum engineering, and PhD candidate Michael G. Taylor. The research, completed in Mpourmpakis’ Computer-Aided Nano and Energy Lab (C.A.N.E.LA.), is funded through a National Science Foundation CAREER award and bridges previous research focused on designing nanoparticles for catalytic applications.

“Even though there is extensive research into metal nanoparticle synthesis, there really isn’t a rational explanation why a nanoparticle is formed,” Dr. Mpourmpakis said. “We wanted to investigate not just the catalytic applications of nanoparticles, but to make a step further and understand nanoparticle stability and formation. This new thermodynamic stability theory explains why ligand-protected metal nanoclusters are stabilized at specific sizes.”

Read more.


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8 years ago

Woahh!!!

The Application Of Sunblock In Visible And UV Light. 
The Application Of Sunblock In Visible And UV Light. 
The Application Of Sunblock In Visible And UV Light. 

The Application of Sunblock in Visible and UV Light. 

(lifepixel)

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