All These Beautiful Scenes And All I Could Think Was "LOOK AT ALL THE SCATTERING" :')

Gone With The Wind

The Myth of Prometheus

Before the creation of humanity, the Greek gods won a great battle against a race of giants called the Titans. Most Titans were destroyed or driven to the eternal hell of Tartarus. But the Titan Prometheus, whose name means foresight, persuaded his brother Epimetheus to fight with him on the side of the gods. 

As thanks, Zeus entrusted the brothers with the task of creating all living things. Epimetheus was to distribute the gifts of the gods among the creatures. To some, he gave flight; to others, the ability to move through water or race through grass. He gave the beasts glittering scales, soft fur, and sharp claws.

Meanwhile, Prometheus shaped the first humans out of mud. He formed them in the image of the gods, but Zeus decreed they were too remain mortal and worship the inhabitants of Mount Olympus from below. Zeus deemed humans subservient creatures vulnerable to the elements and dependent on the gods for protection. However, Prometheus envisioned his crude creations with a greater purpose. So when Zeus asked him to decide how sacrifices would be made, the wily Prometheus planned a trick that would give humans some advantage. He killed a bull and divided it into two parts to present to Zeus. On one side, he concealed the succulent flesh and skin under the unappealing belly of the animal. On the other, he hid the bones under a thick layer of fat. When Zeus chose the seemingly best portion for himself, he was outraged at Prometheus’s deception. 

Fuming, Zeus forbade the use of fire on Earth, whether to cook meat or for any other purpose. But Prometheus refused to see his creations denied this resource. And so, he scaled Mount Olympus to steal fire from the workshop of Hephaestus and Athena. He hid the flames in a hollow fennel stalk and brought it safely down to the people. This gave them the power to harness nature for their own benefit and ultimately dominate the natural order. 

With fire, humans could care for themselves with food and warmth. But they could also forge weapons and wage war. Prometheus’s flames acted as a catalyst for the rapid progression of civilization. When Zeus looked down at this scene, he realized what had happened. Prometheus had once again wounded his pride and subverted his authority. 

Furious, Zeus imposed a brutal punishment. Prometheus was to be chained to a cliff for eternity. Each day, he would be visited by a vulture who would tear out his liver and each night his liver would grow back to be attacked again in the morning. Although Prometheus remained in perpetual agony, he never expressed regret at his act of rebellion. His resilience in the face of oppression made him a beloved figure in mythology. He was also celebrated for his mischievous and inquisitive spirit, and for the knowledge, progress, and power he brought to human hands. 

He’s also a recurring figure in art and literature. In Percy Bysshe Shelley’s lyrical drama “Prometheus Unbound,” the author imagines Prometheus as a romantic hero who escapes and continues to spread empathy and knowledge. Of his protagonist, Shelley wrote, “Prometheus is the type of the highest perfection of moral and intellectual nature, impelled by the purest and the truest motives to the best and noblest ends.” His wife Mary envisaged Prometheus as a more cautionary figure and subtitled her novel “Frankenstein: The Modern Prometheus.” This suggests the damage of corrupting the natural order and remains relevant to the ethical questions surrounding science and technology today. As hero, rebel, or trickster, Prometheus remains a symbol of our capacity to capture the powers of nature, and ultimately, he reminds us of the potential of individual acts to ignite the world.

From the TED-Ed Lesson The myth of Prometheus - Iseult Gillespie

Animation by Léa Krawczyk ( @lea–krawczyk )

(Image caption: Brain showing hallmarks of Alzheimer’s disease (plaques in blue). Credit: ZEISS Microscopy)

New imaging technique measures toxicity of proteins associated with Alzheimer’s and Parkinson’s diseases

Researchers have developed a new imaging technique that makes it possible to study why proteins associated with Alzheimer’s and Parkinson’s diseases may go from harmless to toxic. The technique uses a technology called multi-dimensional super-resolution imaging that makes it possible to observe changes in the surfaces of individual protein molecules as they clump together. The tool may allow researchers to pinpoint how proteins misfold and eventually become toxic to nerve cells in the brain, which could aid in the development of treatments for these devastating diseases.

The researchers, from the University of Cambridge, have studied how a phenomenon called hydrophobicity (lack of affinity for water) in the proteins amyloid-beta and alpha synuclein – which are associated with Alzheimer’s and Parkinson’s respectively – changes as they stick together. It had been hypothesised that there was a link between the hydrophobicity and toxicity of these proteins, but this is the first time it has been possible to image hydrophobicity at such high resolution. Details are reported in the journal Nature Communications.

“These proteins start out in a relatively harmless form, but when they clump together, something important changes,” said Dr Steven Lee from Cambridge’s Department of Chemistry, the study’s senior author. “But using conventional imaging techniques, it hasn’t been possible to see what’s going on at the molecular level.”

In neurodegenerative diseases such as Alzheimer’s and Parkinson’s, naturally-occurring proteins fold into the wrong shape and clump together into filament-like structures known as amyloid fibrils and smaller, highly toxic clusters known as oligomers which are thought to damage or kill neurons, however the exact mechanism remains unknown.

For the past two decades, researchers have been attempting to develop treatments which stop the proliferation of these clusters in the brain, but before any such treatment can be developed, there first needs to be a precise understanding of how oligomers form and why.

“There’s something special about oligomers, and we want to know what it is,” said Lee. “We’ve developed new tools that will help us answer these questions.”

When using conventional microscopy techniques, physics makes it impossible to zoom in past a certain point. Essentially, there is an innate blurriness to light, so anything below a certain size will appear as a blurry blob when viewed through an optical microscope, simply because light waves spread when they are focused on such a tiny spot. Amyloid fibrils and oligomers are smaller than this limit so it’s very difficult to directly visualise what is going on.

However, new super-resolution techniques, which are 10 to 20 times better than optical microscopes, have allowed researchers to get around these limitations and view biological and chemical processes at the nanoscale.

Lee and his colleagues have taken super-resolution techniques one step further, and are now able to not only determine the location of a molecule, but also the environmental properties of single molecules simultaneously.

Using their technique, known as sPAINT (spectrally-resolved points accumulation for imaging in nanoscale topography), the researchers used a dye molecule to map the hydrophobicity of amyloid fibrils and oligomers implicated in neurodegenerative diseases. The sPAINT technique is easy to implement, only requiring the addition of a single transmission diffraction gradient onto a super-resolution microscope. According to the researchers, the ability to map hydrophobicity at the nanoscale could be used to understand other biological processes in future.

Building microfluidic circuits is generally a multi-day process, requiring a clean room and specialized manufacturing equipment. A new study suggests a quicker alternative using fluid walls to define the circuit instead of solid ones. The authors refer to their technique as “Freestyle Fluidics”. As seen above, the shape of the circuit is printed in the operating fluid, then covered by a layer of immiscible, transparent fluid. This outer layer help prevent evaporation. Underneath, the circuit holds its shape due to interfacial forces pinning it in place. Those same forces can be used to passively drive flow in the circuit, as shown in the lower animation, where fluid is pumped from one droplet to the other by pressure differences due to curvature. Changing the width of connecting channels can also direct flow in the circuits. This technique offers better biocompatibility than conventional microfluidic circuits, and the authors hope that this, along with simplified manufacturing, will help the technique spread. (Image and research credit: E. Walsh et al., source)

14-year-old Richard Pierce, Western Union messenger, works from 7 a.m. to 6 p.m, Delaware, 1910

via reddit

Whistler, Canada

Measuring Cosmic Rays at the Edge of Space

It’s a bird!  It’s a plane!  It’s a… SuperTIGER?

No, that’s not the latest superhero spinoff movie - it’s an instrument launching soon from Antarctica! It’ll float on a giant balloon above 99.5% of the Earth’s atmosphere, measuring tiny particles called cosmic rays.

Right now, we have a team of several scientists and technicians from Washington University in St. Louis and NASA at McMurdo Station in Antarctica preparing for the launch of the Super Trans-Iron Galactic Element Recorder, which is called SuperTIGER for short. This is the second flight of this instrument, which last launched in Antarctica in 2012 and circled the continent for a record-breaking 55 days.  

SuperTIGER measures cosmic rays, which are itty-bitty pieces of atoms that are zinging through space at super-fast speeds up to nearly the speed of light. In particular, it studies galactic cosmic rays, which means they come from somewhere in our Milky Way galaxy, outside of our solar system.

Most cosmic rays are just an individual proton, the basic positively-charged building block of matter. But a rarer type of cosmic ray is a whole nucleus (or core) of an atom - a bundle of positively-charged protons and non-charged neutrons - that allows us to identify what element the cosmic ray is. Those rare cosmic-ray nuclei (that’s the plural of nucleus) can help us understand what happened many trillions of miles away to create this particle and send it speeding our way.

The cosmic rays we’re most interested in measuring with SuperTIGER are from elements heavier than iron, like copper and silver. These particles are created in some of the most dynamic and exciting events in the universe - such as exploding and colliding stars.

In fact, we’re especially interested in the cosmic rays created in the collision of two neutron stars, just like the event earlier this year that we saw through both light and gravitational waves. Adding the information from cosmic rays opens another window on these events, helping us understand more about how the material in the galaxy is created.

Why does SuperTIGER fly on a balloon?

While cosmic rays strike our planet harmlessly every day, most of them are blocked by the Earth’s atmosphere and magnetic field.  That means that scientists have to get far above Earth - on a balloon or spacecraft - to measure an accurate sample of galactic cosmic rays.  By flying on a balloon bigger than a football field, SuperTIGER can get to the edge of space to take these measurements.  

It’ll float for weeks at over 120,000 feet, which is nearly four times higher than you might fly in a commercial airplane. At the end of the flight, the instrument will return safely to the ice on a huge parachute. The team can recover the payload from its landing site, bring it back to the United States, repair or make changes to it, if needed, and fly it again another year!

There are also cosmic ray instruments on our International Space Station, such as ISS-CREAM and CALET, which each started their development on a series of balloons launched from Antarctica. The SuperTIGER team hopes to eventually take measurements from space, too.  

Why do we launch from Antarctica?

McMurdo Station is a hotspot for all sorts of science while it’s summer in the Southern Hemisphere (which is winter here in the United States), including scientific ballooning.  The circular wind patterns around the pole usually keep the balloon from going out over the ocean, making it easier to land and recover the instrument later. And the 24-hour daylight in the Antarctic summer keeps the balloon at a nearly constant height to get very long flights - it would go up and down if it had to experience the temperature changes of day and night. All of that sunlight shining on the instrument’s array of solar cells also gives a continuous source of electricity to power everything.

Antarctica is an especially good place to fly a cosmic ray instrument like SuperTIGER. The Earth’s magnetic field blocks fewer cosmic rays at the poles, meaning that we can measure more particles as SuperTIGER circles around the South Pole than we would at NASA scientific ballooning sites closer to the Earth’s equator.  

The SuperTIGER team is hard at work preparing for launch right now - and their launch window opens soon! Follow @NASABlueshift for updates and opportunities to interact with our scientists on the ice.

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

Unusual Insects Taking Off

What do you do when you’re an insect researcher with a high-speed camera? Why, film all sorts of unusual insects from your backyard as they take off and fly! (Image and video credit: Ant Lab/A. Smith; via Colossal) Read the full article

Self-assembling particles brighten future of LED lighting

Just when lighting aficionados were in a dark place, LEDs came to the rescue. Over the past decade, LED technologies – short for light-emitting diode – have swept the lighting industry by offering features such as durability, efficiency and long life.

Now, Princeton engineering researchers have illuminated another path forward for LED technologies by refining the manufacturing of light sources made with crystalline substances known as perovskites, a more efficient and potentially lower-cost alternative to materials used in LEDs found on store shelves.

The researchers developed a technique in which nanoscale perovskite particles self-assemble to produce more efficient, stable and durable perovskite-based LEDs. The advance, reported January 16 in Nature Photonics, could speed the use of perovskite technologies in commercial applications such as lighting, lasers and television and computer screens.

“The performance of perovskites in solar cells has really taken off in recent years, and they have properties that give them a lot of promise for LEDs, but the inability to create uniform and bright nanoparticle perovskite films has limited their potential,” said Barry Rand an assistant professor of electrical engineering and the Andlinger Center for Energy and the Environment at Princeton.

Read more.