She didn’t have to flex this hard 😤😤
After the Battle of Shiloh in 1862, many Civil War soldiers’ lives were saved by a phenomenon called ‘Angel’s Glow.’ The soldiers, who lay in the mud for two rainy days, had wounds that began to glow in the dark and heal unusually fast. In 2001, 2 teens won an international science fair by discovering the soldiers had been so cold that their bodies created the perfect conditions for growing a bioluminescent bacteria, which ultimately destroyed the bad bacteria that could’ve killed them. Source Source 2 Source 3
Words matter when talking about Alzheimer’s
Using war metaphors in reference to Alzheimer’s disease should be replaced with messages of resilience against a complex, age-associated condition that may not be fully defeatable, according to a team of researchers.
Framing a health issue through comparisons to warfare is common in popular media and medical and research communities. While it can motivate efforts to deal with the issue, this type of language and messaging can also create fear and stigma, turn patients into victims and divert resources from critically important prevention and care, said Daniel R. George, assistant professor of medical humanities, Penn State College of Medicine.
Despite decades of failures in Alzheimer’s drug development, scientific attention continues to focus on drugs that “attack” a molecular compound called beta amyloid, with the goal of curing the disease. Amyloid is a key component of the plaques in the brain that are a hallmark of Alzheimer’s disease. Research, however, shows that the appearance of amyloid does not correlate with clinical symptoms and beta amyloid has repeatedly been found in the brains of one-third of “normal” elderly people. This suggests that amyloid may be a symptom rather than a cause of damage. A growing number of researchers believe that declaring “war” on Alzheimer’s by “attacking” amyloid may ultimately be an exercise in self-harm, particularly if amyloid is representative of the brain’s repair response, and may be channeling resources away from other drug-based approaches that do not assume amyloid toxicity.
Scholars have argued that metaphors and narratives that treat disease as something to be attacked can be socially damaging to those affected. The value of such metaphors may be clearer for infectious diseases caused by single pathogens. It becomes more problematic when discussing diverse, age-associated syndromes like Alzheimer’s that may not be fully curable. In this way, war metaphors in medicine can invite ways of thinking that may not be scientifically or socially productive.
“If applied in a careless manner, war metaphors can delude our sense of what’s possible therapeutically, and give false hope to people and caregivers who are suffering,” George said.
George and his co-authors propose moving toward different types of metaphors – those that encourage use of words like “slow” or “postpone” rather than “prevent” or “cure,” and emphasize building “resilience” to aging processes in the brain rather than aiming at “absolute victory” over a disease. While “fighting” and “defeating” Alzheimer’s through drug development is important, the authors argue it may be wiser to acknowledge that Alzheimer’s is not a disease disconnected from the aging process like polio or malaria. The authors note that Alzheimer’s has been classified as a disease for the past 40 years. They suggest it may be more beneficial to take a lifespan-oriented approach that includes education about known biological, psychosocial and environmental risk factors, investment in societal programs and infrastructure that support brain health, and ensuring proper care for those affected and their caregivers.
“While not as profitable as drug development, public health initiatives that reduce vascular risk factors, modulate oxidative stress and inflammation, guard against traumatic brain injuries, promote social engagement and lifelong learning, and reduce exposure to neurotoxins, and other commonsense actions should be an explicit component of our societal response (to Alzheimer’s),” the researchers wrote in the American Journal of Bioethics.
George drew particular attention to the residents of Flint, Michigan being exposed to lead, a neurotoxin, through the water supply.
“It is inexcusable that we could let our public infrastructure fail to the point where it becomes a contributor to Alzheimer’s disease risk for socio-economically disadvantaged citizens,” George said. “If we’re really serious about addressing the problem of Alzheimer’s, we must start by not poisoning our citizens.”
Moving beyond the notion of being at war against Alzheimer’s could also serve to humanize cognitive aging.
“There’s a widely-accepted myth that people who have Alzheimer’s are sort of non-people, akin to zombies,” George said. “There are ways to construct meaning around memory loss that show greater compassion and solidarity toward people with cognitive frailty rather than seeing them as passive victims in our biological war against the disease. We believe in a more humane message – that even if you have a diagnosis of ‘probable Alzheimer’s’ you can still have a life with deep purpose, social contribution and meaningful relationships.”
As Ars has reported previously, scientists have found that triclosan and other antimicrobial soaps have little benefit to consumers and may actually pose risks. These include bolstering antibiotic resistant microbes, giving opportunistic pathogens a leg up, and disrupting microbiomes. In its final ruling, issued Friday, the FDA seemed to agree. “Consumers may think antibacterial washes are more effective at preventing the spread of germs, but we have no scientific evidence that they are any better than plain soap and water,” Janet Woodcock, director of the FDA’s Center for Drug Evaluation and Research (CDER), said in a statement. “In fact, some data suggests that antibacterial ingredients may do more harm than good over the long-term.”
[…]
The ruling does not affect alcohol-based hand sanitizers or wipes, which the agency is reviewing separately. It also does not affect antiseptic products used in healthcare settings.
My tummy is blushing now.
People Were Asked: ‘What’s The Coolest Thing Most People Don’t Know About Their Own Body?’
Scientists have discovered the world’s oldest known water in an ancient pool in Canada that’s at least 2 billion years old.
Back in 2013 they found water dating back about 1.5 billion years at the Kidd Mine in Ontario, but searching deeper at the site revealed an even older source buried underground.
The initial discovery of the ancient liquid in 2013 came at a depth of around 2.4 kilometres (1.5 miles) in an underground tunnel in the mine. But the extreme depth of the mine – which at 3.1 kilometres (1.9 miles) is the deepest base metal mine in the world – gave researchers the opportunity to keep digging.
“[The 2013 find] really pushed back our understanding of how old flowing water could be and so it really drove us to explore further,” geochemist Barbara Sherwood Lollar from the University of Toronto told Rebecca Morelle at the BBC.
“And we took advantage of the fact that the mine is continuing to explore deeper and deeper into the earth.”
The new source was found at about 3 kilometres (1.9 miles) down, and according to Sherwood Lollar, there’s a lot more of it than you might expect.
Continue Reading.
Have you ever seen a Lybia crab? Often called boxer crabs, or pom-pom crabs, these tiny crustaceans are easily identified by a unique behavior: they hold anemones on their claws to defend themselves from predators, keeping the anemones small enough to wield by limiting their food intake. But how do they get the anemones in the first place? Researchers think they have an answer: by stealing one from another crab, and then splitting it in half to create two identical clones—one for each claw.
Two graduate students, Yisrael Schnytzer and Yaniv Giman, set out to discover how the Lybia crabs acquire their anemones. They spent years observing and collecting crabs (Lybia leptochelis, specifically) from the Red Sea. Given that Lybia crabs are exceptionally well-camouflaged and only a few centimeters across, this was no easy task, but they managed to observe or collect more than 100 individuals.
Every specimen Schnytzer and Giman found was in possession of a pair of anemones, and each anemone belonged to the genus Alicia. Interestingly, the anemones themselves were not found living by themselves; they were only found already living on the claws of Lybia crabs. The researchers decided to study some of the crabs in a laboratory, to see if more observation would solve the mystery of how they acquired their anemones to begin with.
In the lab, the researchers conducted several experiments, the first of which was to take one anemone away from a crab. When left with just one anemone, the crab solved the problem by splitting the remaining anemone into two. The two halves of the anemone would then regenerate into two identical clones, one for each claw, over the course of several days.
The second experiment involved removing both anemones from one crab and placing it in a tank with a crab that still had both its anemones. The result: the two crabs would fight, with the anemone-less crab usually succeeding in stealing one anemone from the other crab. These fights did not tend to result in injuries to the crabs themselves, and once each crab was in possession of one anemone, both crabs would split their anemone into halves to create a pair of clones.
In addition to these experiments, Schnytzer and Giman examined the genes of the anemones found on the wild crabs. Every crab collected from the wild was holding a pair of identical clones. This might mean that anemone theft is rampant among Lybia crabs in the Red Sea, and that it might be the main way that these crabs acquire their anemones.
At any rate, it is clear that the crabs are frequently splitting anemones in two, inducing asexual reproduction in another species and potentially limiting that species’ genetic diversity in the process—a rarity outside the human world.
Based on materials provided by PeerJ and ScienceDaily
Journal reference: Yisrael Schnytzer, Yaniv Giman, Ilan Karplus, Yair Achituv. Boxer crabs induce asexual reproduction of their associated sea anemones by splitting and intraspecific theft. PeerJ, 2017; 5: e2954 DOI: 10.7717/peerj.2954
Image credit: Yisrael Schnytzer
Submitted by volk-morya
Women scientists made up 25% of the Pluto fly-by New Horizon team. Make sure you share this, because erasing women’s achievements in science and history is a tradition. Happens every day.
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http://pluto.jhuapl.edu/News-Center/News-Article.php?page=20150712
Fascinating, even if you are unable to grasp the mathematical depths, details are for professional thinkers on the field, enjoy the surface, is pretty enjoyable too.
A surprising new proof is helping to connect the mathematics of infinity to the physical world. (Quanta Magazine)
Images by Lucy Reading-Ikkanda