Fyi For Those In Phoenix Arizona: Stay Away From Target Because The Phoenix Police Still Won't Arrest

like i'm sorry but we as a fandom have to stay firm on our anti-AI values. we cannot suddenly start giving AI a pass when it's something we "want to see" like destiel kisses. it's not suddenly fine. we're not going to start using AI to make fanfic scenes come to life or audio AI to make characters "say" stuff we want to hear. you have GOT to be firm on your anti-AI stance. if you start making exceptions then suddenly anything will fly. fandom is for real art and creations made by real people. no AI fanfics. no AI art. no AI rendered "bonus" scenes. no AI audio. none of it has a place here.

WALT DISNEY PRODUCTION WORKERS NEED YOUR HELP!

Hey fam! The Mouse is refusing to recognize the unionization efforts of its production workers. If you're not familiar with what PAs or PMs do, I'll outline it briefly. The tl;dr is that NO ANIMATION WOULD GET DONE WITHOUT PRODUCTION WORKERS. They are the glue holding together every single production of your very favorite cartoons!

They take notes in all the meetings with the artists.

They make sure the artists are meeting their deadlines (and showing up to the meetings in the first place).

They help us navigate studio servers to find the files we're looking for.

They send us our time cards, and make sure we get paid!

Production workers do all this and more, often for minimum wage. The hardships that they suffer as a result--the long hours, the unpaid overtime, the abuses of power--are horrific.

You'd really think that they'd be compensated fairly for these jobs! Can you imagine trying to live in Los Angeles or New York on minimum wage with a job that definitely won't allow you time to pick up a second or third one??

This has to stop, and you can help.

All that Walt Disney Animation Studio's production workers ask is that you add your name to this petition! That's it.

This isn't some Change.org petition. It's not going to sell your email to spam companies. This is through IATSE (our union)'s website.

TELL DISNEY YOU STAND WITH PRODUCTION WORKERS!!!

In case any of you here also use X/Twitter.

Skip Google for Research

As Google has worked to overtake the internet, its search algorithm has not just gotten worse.  It has been designed to prioritize advertisers and popular pages often times excluding pages and content that better matches your search terms 

As a writer in need of information for my stories, I find this unacceptable.  As a proponent of availability of information so the populace can actually educate itself, it is unforgivable.

Below is a concise list of useful research sites compiled by Edward Clark over on Facebook. I was familiar with some, but not all of these.

⁂

Google is so powerful that it “hides” other search systems from us. We just don’t know the existence of most of them. Meanwhile, there are still a huge number of excellent searchers in the world who specialize in books, science, other smart information. Keep a list of sites you never heard of.

www.refseek.com - Academic Resource Search. More than a billion sources: encyclopedia, monographies, magazines.

www.worldcat.org - a search for the contents of 20 thousand worldwide libraries. Find out where lies the nearest rare book you need.

https://link.springer.com - access to more than 10 million scientific documents: books, articles, research protocols.

www.bioline.org.br is a library of scientific bioscience journals published in developing countries.

http://repec.org - volunteers from 102 countries have collected almost 4 million publications on economics and related science.

www.science.gov is an American state search engine on 2200+ scientific sites. More than 200 million articles are indexed.

www.pdfdrive.com is the largest website for free download of books in PDF format. Claiming over 225 million names.

www.base-search.net is one of the most powerful researches on academic studies texts. More than 100 million scientific documents, 70% of them are free

Now more than ever we need to make Tumblr unmarketable, do NOT invite the government into this space.

The Secret of NIMH, 1982

don't give up

Good News Network

Researchers Discover New Mechanism for Rapid Liver Regeneration to Restore Damaged Livers

Researchers discovered a mechanism after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

"Researchers at the National Cancer Research Centre in Spain (CNIO) have discovered a mechanism that is triggered just minutes after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

The avenues for future treatments of liver damage include a diet enriched with the amino acid glutamate.

“Glutamate supplementation can promote liver regeneration and benefit patients in recovery following hepatectomy or awaiting a transplant,” wrote the authors in a paper published in ‘Nature’.

The liver is a vital organ, crucial to digestion, metabolism, and the elimination of toxins. It has a unique ability to regenerate, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.

However, the liver stops regenerating in cases of diseases that involve chronic liver damage–such as cirrhosis—and such diseases are becoming increasingly prevalent, associated with poor dietary habits or alcohol consumption. So activating liver regeneration is key to treating the disease.

Learning to activate liver regeneration is therefore a priority today, to benefit patients with liver damage and also those who’ve had part of their liver cut out to remove a tumor.

The research has discovered in animal models this previously unknown mechanism of liver regeneration. It is a process that is triggered very quickly, just a few minutes after acute liver damage occurs, with the amino acid glutamate playing a key role.

“Our results describe a fundamental and universal mechanism that allows the liver to regenerate after acute damage,” explained Nabil Djouder, head of the CNIO Growth Factors, Nutrients and Cancer Group and senior author of the study.

A “complex and ingenious” perspective on liver regeneration

Liver regeneration was known to occur through the proliferation of liver cells, known as hepatocytes. However, the molecular mechanisms involved were not fully understood. This current discovery is very novel, as it describes communication between two different organs, the liver and bone marrow, involving the immune system, according to a CINO news release.

The results show that liver and bone marrow are interconnected by glutamate. After acute liver damage, liver cells, called hepatocytes, produce glutamate and send it into the bloodstream; through the blood, glutamate reaches the bone marrow, inside the bones, where it activates monocytes, a type of immune system cell. Monocytes then travel to the liver and along the way become macrophages – also immune cells. The presence of glutamate reprograms the metabolism of macrophages, and these consequently begin to secrete a growth factor that leads to an increase in hepatocyte production.

In other words, a rapid chain of events allows glutamate to trigger liver regeneration in just minutes, through changes in the macrophage metabolism. It is, says Djouder, “a new, complex and ingenious perspective on how the liver stimulates its own regeneration.”

The research also clarifies a previously unanswered question: how the various areas of the liver are coordinated during regeneration. In the liver, there are different types of hepatocytes, organized in different areas; the hepatocytes in each area perform specific metabolic functions. The study reveals that hepatocytes producing a protein known as glutamine synthetase, which regulates glutamate levels, play a key role in regeneration.

According to the CNIO group, when glutamine synthetase is inhibited, there is more glutamate in circulation, which accelerates liver regeneration. This is what happens when the liver suffers acute damage: glutamine synthase activity decreases, blood glutamate increases, and from there, the connection with the bone marrow is established, reprogramming macrophages and stimulating hepatocyte proliferation.

Possible therapeutic applications

The experiments have been carried out in mice, but the results have been tested with bioinformatics tools, using databases of mouse and human hepatocytes.

According to Djouder, “dietary glutamate supplementation may simply be recommended in the future after liver extirpation, and also to reduce liver damage caused by cirrhosis.”

The first author of the paper, CNIO researcher María del Mar Rigual also wants future research to explore using glutamate supplements in humans who have undergone liver resection for tumor removal."

-via Good News Network, March 30, 2025

I realize this is a new blog and not a lot of people might not see this but what the hell.

Happy Birthday to me.