Myeloblasts In AML

It shifts

Grief

I don’t know how or when

But at some point

The happy memories

Become more of a comfort

Than a pain

Not every day

And not all the time

But some days

Grief shifts

Type B orcas surfacing

Natgeo

Just found out about the weirdest shark ever

Prickly dogfish

Take a look at this newly diagnosed Multiple

Myeloma (MM) case!

MM is a type of cancer developed by the overproduction of plasma cells in the bone marrow (B-cell lineage). Plasma cells are responsible for the production of antibodies to fight infection within the body.

Helpful lab findings

C- hypercalcemia

R- renal failure (increased CREA+BUN)

A- anemia

B- bone lesions

Confirmatory testing

1. Serum protein electrophoresis: spike in the gamma wave aka monoclonal paraprotein (M-spike)

2. Immunofixation protein electrophoresis: identifies the type of immunoglobulin (heavy chain) present (IgA, IgG, [gE, etc.)

3. Free Light Chain Assay: determine if the immuglobulin is

Kappa or Lambda

4. Bone Marrow aspiration: take a look at the first picture.

60% of the bone marrow is most likely plasma cells

Different types of MM

-Smoldering MM (increased plasma cells in bone marrow & high protein. Does NOT follow CRAB)

-MGUS (decreased plasma cells in bone marrow)

-Light chain amyloidosis

ID credit: divingfirst on 小红书

(please like, reblog and give proper credit if you use any of my gifs!)

Leaf epidermis under dark (top) and light (bottom) condition. Stomatal openings seen on both picture.  

Check out these crystals I found in an acidic urine - uric acid crystals?

#Microbes

Today’s Friend from Borneo is the Bornean Tree-hole Frog (Metaphrynella sundana)! He is singing his Beautiful Song from his hole in the middle of a tree! (Bonus Crested Toad (Ingerophrynus divergens)!)

A new giant-screen film is on view in the Museum’s LeFrak Theater, starting today! In Turtle Odyssey, discover the wondrous life of a sea turtle named Bunji, from hatchling to adulthood, and the great migration undertaken by generations before her. As this turtle leaves the rookery on the Great Barrier Reef and swims hundreds of miles, she encounters many marine animals—including humpback whales, parrot fish, and even a great white shark—as well as threats to her survival, like plastic waste.

Beat the heat, visit the Museum, and enjoy this immersive giant-screen film on a 40-foot-high, 66-foot-wide screen with state-of-the-art digital sound!