Thanks For Making This Awesome Activity @yuu-chii I Crossed Out Lots More Than I Thought I Would And

Finished my first memo! Need a chai to sooth my anxiety over my future grade 💖

hello!

I’m Anna - I’ve recently restarted running my studyblr in the hopes of it helping me motivate myself and help me take an initiative in being more organized for the new year. Hopefully I’ll meet some new people in the community and we can be friends!

about me:                                                                                                                        - I love tomatoes                                                                                                     - I love running (short distance)                                                                                                  - I just recently started highschool                                                                                                  - Yellow is my fav color                                                                                                  - I speak Russian and English                                                                                                  - I can play the ukulele                                                                                                - I live for memes 

*  if we have anything in common, message me! we can bond ha *

my fav studyblrs 

@cloudedstudy - @studyblr - @studign - @emmastudies  - @acadmia - @physike - @wildliners - @intellectys - @studynine - @stu-pidest - @teacomets - @sadgirlstudying - @no-cake-where - @hannahstudies - @studythetics - @revisoin - @aou - @studyisms - @altairstudy - @minimalismstudies

pls reblog or like if you’re a studyblr, I’m always looking for new studyblr accounts to follow. 

hope you all had a great 2017 and have an even better 2018!

Study identifies new target to preserve nerve function

Scientists in the Vollum Institute at OHSU have identified an enzyme that plays a crucial role in the degeneration of axons, the threadlike portions of a nerve cell that transmit signals within the nervous system. Axon loss occurs in all neurodegenerative diseases, so this discovery could open new pathways to treating or preventing a wide array of brain diseases.

The research team discovered a new role of the enzyme Axundead - or Axed - in promoting the self-destruction of axons. They found that when Axed function was blocked, injured axons not only maintained their integrity but remained capable of transmitting signals within the brain’s complex circuitry for weeks. Their research was published July 5 in the journal Neuron.

“If you target this pathway, you have a really good chance of preserving the functional aspects of neurons after a variety of types of trauma or injury,” said senior author Marc Freeman, Ph.D., director of the Vollum Institute at OHSU. “It’s a very attractive therapeutic target.”

Freeman conducted the work in the Department of Neurobiology at the University of Massachusetts Medical School. He has since been recruited to head the Vollum Institute, which conducts cutting-edge basic research into how the nervous system works at a molecular level.

Severing axons, or axotomy, is a simple way to study the molecular basis of neurodegeneration as it leads to the activation of explosive axonal degeneration. In the laboratory, researchers using this technique can identify pro-degenerative genes with great specificity, especially when using sophisticated genetic approaches in the fruit fly Drosophila, Freeman’s primary research model organism. Drosophila shares these same pathways with humans. Previous work by Freeman’s lab identified another enzyme, a gene called SARM, which was the first shown to activate a process that causes axons to disintegrate when damaged.

In the current study, Freeman and colleagues identified Axed, showed that it functions downstream of SARM to execute axonal degeneration, and, surprisingly, that the protection afforded by blocking Axed was even stronger than SARM.

“There was really nothing we could do to kill axons where Axed function was blocked,” Freeman said.

From an evolutionary perspective, Freeman said SARM and Axed function are likely important in the peripheral nervous system after injury because programmed axon death allows for efficient packaging of damaged cellular materials for removal by immune cells. This process thereby clears the pathway for new neuronal processes to regrow, reinnervate tissues, and recover function.

From a therapeutic perspective, the goal of the work is to understand at the molecular level how axons degenerate, and block those pathways in patients to preserve nervous system function. In many nervous system injuries axons are not severed but become stretched or crushed, which activates the SARM-dependent death program and drives axon loss. In those cases, it’s imperative to block SARM and Axed signaling to preserve axon integrity, and in turn neuronal function. At the same time, Freeman and others have shown that SARM-dependent signaling pathways also drive axon loss in neurodegenerative conditions including glaucoma, traumatic brain injury and peripheral neuropathy. This suggests the notion of an ancient and conserved axon death signaling pathway that is widely activated to drive axon loss. Since axon loss is a universal feature of neurodegenerative diseases, it seems likely that blocking this pathway could have enormous therapeutic benefit.

“If we can find ways to block it, maybe we can preserve function in a wide array of patients who have lost axons through neurodegenerative diseases or other neural trauma,” Freeman said.

english essays would be way cooler if they’d teach us to be just, super critical of classic literature 

imagine if the standard teaching approach to essays was more along the lines of “here’s an outdated written work by a member of the ruling class of a society that was conspicuously more prejudiced than ours. use textual examples to demonstrate why it would be hella inappropriate and probably quite shitty to publish-glorify today.

confusing but cool,, productive day studying chemistry!! q - do yall think i shld do the 100 days of productivity challenge? let me know in the comments!!

:)

12•12•17

2/100 My anatomy study guide for the final: done! The final itself is tomorrow as well as my geometry one. Super nervous, but confident I can do well! Also: my notecard I can use for the anatomy final! I wrote very tiny. 🎧Crime - Skott, Grey

Physics time!

I was gonna do my laundry but when I turned the corner and saw this on the ground I stopped what I was doing and decided to make a snapchat story of science (I’m @thescalex on snapchat, if you want my username)

*cue Charlie Brown soundtrack of kids cheering*

There’s your science for the day. Go try it out for yourself!

*UPDATED* in the final picture of the original post, I made the mistake of saying “light as a particle” - I should have repeated the initial description (which is now fixed): the effect is from light passing through a single slit and diffracting, which is more accurate to what is being observed, because each bulb is a “point-source of light.” While the general scientific consensus is that light does indeed have particle properties, this single slit experiment is not a true depictor of those properties. While fewer photons do indeed get through, diffraction still (faintly) occurs between the lines. It’s the double slit experiment where things get REALLY weird, though.

this user has marfan syndrome

ya know what I want to see more of in the study/bujo community

I want to see more dark photos.

I want to see more photos with diverse, colourful, and interesting backgrounds.

I want to see more notes written in ballpoint

I want to see more of the rushed bujo pages made because you didn’t have time to do it but didn’t want to have that week missing from your journal

I want to see more in-class notes, the notes you took before you re-wrote them to make them “post worthy”

I want to see more messy desks. The aftermatch of journaling and studying

I want to see more wooden desks, more desks that aren’t white, more desks covered in coffee rings and paint splats

I want to see more on the fly photos

And I’m not writing this because I want to support “small accounts” or “poor study accounts” I want to see it because I’m sick of every single post looking the same as the one I saw last. I’m tired of accounts with amazing content not getting the growth they deserve because their photos aren’t overexposed on white desks. I want to see it because it stands out, it’s different, and I like it.

So many accounts quit before they even get started because of the precedent that you have to have expensive stationery and stark white photos to grow and make an impact. Because they don’t feel they can live up to the expectations of the community. And that makes me really sad.