What Is Dark Matter? It Is An Invisible Matter That Is Known For Its Lens Effect And Its Anisotropy,

I’ve been on break for a week and a half and I am so ready to go back to school. I’m so bored and so ready to start the semester. Anyone else?

❄ ! january monthly spread ! ❄

i like the minimalistic design of this one. i think the paper cranes (and the whale of course) add some velvet feeling to it (don’t mind my words lol).

on the left page is my ‘random idea bank’. basically you just write any ideas that come to your mind down and see if they develop into something further on, hahah. i think it’s a good way to sort out your thoughts ^-^

01/10/2017 :: Got a lot of work done this afternoon and went for a quick sprint session afterwards too.

this user has marfan syndrome

26.05.18 | tuesday | 6/100 days of productivity here’s my Mess ™ feat. DNA notes. sometimes i stress out over how little i achieve but then i remember that everyone’s speed is different and that’s okay! today i studied DNA and RNA and did some trigonometry practice. also i did some bio tests in the format of my state exam an the result was surprisingly good - i scored 40-something points when i actually don’t know anything - my goal is to make it at least 80 points in one year and a half.

MoonAlchemy’s 2018 Beltane inspired Giveaway! 

This giveaway is in no affiliated with Tumblr. 

Hello, everyone! I have been waiting for the right time to begin this giveaway, and today is that day! I have collected some Beltane inspired items that are just begging to fin a place on someone’s altar. 

RULES: 

You MUST be following me.

Think of something you are grateful for in your life. (feel free to send it to me in a message, or tell someone you care about!)

Only reblogs count.

DO NOT tag as a giveaway.

Extra entry: Favorite my Etsy shop, or an item if you already do! (message me your username on here!)

No giveaway accounts, and please don’t spam your followers!

Only open to U.S. residents, sorry!

Winner chosen on April 25, 2018! 

What you can win:

Three chime candles (red, yellow and green)

One succulent tea light. 

One Quartz point.

One piece of Rose Quartz

One piece of natural Citrine

A super awesome full sized chalice

Faux Dahlias

Large Vials of Rosemary, Basil, and Rose Petals 

Handmade necklace with faux florals inside. 

One full Celtic Cross tarot card reading from me! 

Thank you for your continued support and have fun!

iPad Pro Notes w/ Goodnotes

02/01/2017

⭐️ Starting on my physics study guide! I’m actually really excited about getting back to school, so a bit of a routine is established. I’m a creature of habit, so knowing that there are assigned tins blocks for me to do things in really helps with keep my mood and life level.

I’m liking the Earth-tone aesthetic I’ve got going on here, so I think I might apply it to other projects in the future!

Supplies used: - Staedtler marsgraphic duo in fawn and flesh - Tombow ABT in 977 - Pigma Micron 005 in black

Study identifies new target to preserve nerve function

Scientists in the Vollum Institute at OHSU have identified an enzyme that plays a crucial role in the degeneration of axons, the threadlike portions of a nerve cell that transmit signals within the nervous system. Axon loss occurs in all neurodegenerative diseases, so this discovery could open new pathways to treating or preventing a wide array of brain diseases.

The research team discovered a new role of the enzyme Axundead - or Axed - in promoting the self-destruction of axons. They found that when Axed function was blocked, injured axons not only maintained their integrity but remained capable of transmitting signals within the brain’s complex circuitry for weeks. Their research was published July 5 in the journal Neuron.

“If you target this pathway, you have a really good chance of preserving the functional aspects of neurons after a variety of types of trauma or injury,” said senior author Marc Freeman, Ph.D., director of the Vollum Institute at OHSU. “It’s a very attractive therapeutic target.”

Freeman conducted the work in the Department of Neurobiology at the University of Massachusetts Medical School. He has since been recruited to head the Vollum Institute, which conducts cutting-edge basic research into how the nervous system works at a molecular level.

Severing axons, or axotomy, is a simple way to study the molecular basis of neurodegeneration as it leads to the activation of explosive axonal degeneration. In the laboratory, researchers using this technique can identify pro-degenerative genes with great specificity, especially when using sophisticated genetic approaches in the fruit fly Drosophila, Freeman’s primary research model organism. Drosophila shares these same pathways with humans. Previous work by Freeman’s lab identified another enzyme, a gene called SARM, which was the first shown to activate a process that causes axons to disintegrate when damaged.

In the current study, Freeman and colleagues identified Axed, showed that it functions downstream of SARM to execute axonal degeneration, and, surprisingly, that the protection afforded by blocking Axed was even stronger than SARM.

“There was really nothing we could do to kill axons where Axed function was blocked,” Freeman said.

From an evolutionary perspective, Freeman said SARM and Axed function are likely important in the peripheral nervous system after injury because programmed axon death allows for efficient packaging of damaged cellular materials for removal by immune cells. This process thereby clears the pathway for new neuronal processes to regrow, reinnervate tissues, and recover function.

From a therapeutic perspective, the goal of the work is to understand at the molecular level how axons degenerate, and block those pathways in patients to preserve nervous system function. In many nervous system injuries axons are not severed but become stretched or crushed, which activates the SARM-dependent death program and drives axon loss. In those cases, it’s imperative to block SARM and Axed signaling to preserve axon integrity, and in turn neuronal function. At the same time, Freeman and others have shown that SARM-dependent signaling pathways also drive axon loss in neurodegenerative conditions including glaucoma, traumatic brain injury and peripheral neuropathy. This suggests the notion of an ancient and conserved axon death signaling pathway that is widely activated to drive axon loss. Since axon loss is a universal feature of neurodegenerative diseases, it seems likely that blocking this pathway could have enormous therapeutic benefit.

“If we can find ways to block it, maybe we can preserve function in a wide array of patients who have lost axons through neurodegenerative diseases or other neural trauma,” Freeman said.

They can flip off this country all they want considering the fact it was theirs first.