Artist: Ralph Andres Title: Pikapool “This Is An Old Work About A Mash-up Between Two Of My Favorite

May the Fourth be with you!

Jack: Today’s question is, how do you deal with a crush?

Sam, Cas, Gabe, Dean: *facepalm* not again

Jack: yes again. So dads, what do you do when you have a crush?

Sam, takes the lead to do a little teaching of good values and crap: well, Jack, what I try to do is understand my feelings before I talk to them, and when I do approach them, I am always respectful and mindful of their wishes and I tell them how I feel and compliment them -

Dean, snickering: yeah, right

Sam: Shut up Dean.

Dean: why you gotta lie to the kid, Sammy? We all know that when you have a crush, you get as far away from the person as you can, otherwise they’d start liking you back and then you two’d end up banging and ta-da, they’re dead

Sam: …I hate you

Dean: *shrugs*

Jack, nodding and absorbing: what about you, Dean?

Dean, promptly: Well what you gotta do is judge if they’re in your league or not

Jack: if they are?

Dean: you put on the charm. Remember the blue-steel I showed you once?

Jack: the face I caught you practising in the mirror and you begged me to forget, but I never did?

Dean: yeah that’s the one

Jack: and what if they aren’t in my league?

Dean: you wait for the crush to go away

Jack, nodding: how long does that take?

Dean: depends on a lot of factors. Could be a week, or could be -

Sam, interrupting with a smirk: 10 years, inclusive of time spent in other realms such as purgatory

Jack: that LONG?

Sam, smirking wider as Dean goes red: oh yeah Jack, 10 years and running

Jack, nodding and accepting: I see. What about you, Castiel?

Cas: I…*thinks about raising Dean from hell, rebelling, fighting his garrison, falling from grace, disobeying Naomi, disobeying direct orders from Heaven, choosing him over an entire army, annoying a cosmic being enough to be brought back, healing every little bruise on his perfect face* I believe in grand gestures, Jack

Dean: *narrowing his eyes*

Sam, feeling pity for his brother: No Cas, you don’t. You’re a deathbed-confession guy

Cas: oh yes. That.

Jack, nodding: cool.

Cas, wistfully: but that didn’t work either so I don’t know if anything ever will.

Jack: why don’t you try doing something he likes with him?

Cas, touchy about the topic: You mean, like, cowboy around with him with a hat? Dress up as a medical practitioner to satisfy his kinks?

Dean, growing suspicious: that’s weirdly specific Cas

Cas: I can’t eVEN

~

BONUS

Jack: what about you, uncle Gabe? What do you do when you have a crush?

Gabriel, thinking about all the weird shit he’s done to Sam, ranging from killing his brother 104 times in a day to picking his side over the rest of his family’s, from giving him genital herpes to making him suffer in Nutcracker, and so on and so forth: heh

Jack: what?

Gabriel: …archangels don’t get crushes hehe

Jack, nodding: okay thanks

*in another corner of the room*

Dean and Cas, at the same time: its okay Sam - NO - DON’T try to strangle yourself it’s fine he’s just dodging the question - nO SAM don’t try to strangle him either - sAM you’re scaring us now please start b r e a t h i n g

Hey, here’s that life-saving height difference photo you needed.

Embryo stem cells created from skin cells

Researchers at the Hebrew University of Jerusalem (HU) have found a way to transform skin cells into the three major stem cell types that comprise early-stage embryos. The work (in mouse cells) has significant implications for modelling embryonic disease and placental dysfunctions, as well as paving the way to create whole embryos from skin cells.

As published in Cell Stem Cell, Dr. Yossi Buganim of HU’s Department of Developmental Biology and Cancer Research and his team discovered a set of genes capable of transforming murine skin cells into all three of the cell types that comprise the early embryo: the embryo itself, the placenta and the extra-embryonic tissues, such as the umbilical cord. In the future, it may be possible to create entire human embryos out of human skin cells, without the need for sperm or eggs. This discovery also has vast implications for modelling embryonic defects and shedding light on placental dysfunctions, as well as solving certain infertility problems by creating human embryos in a petri dish.

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