from letterarii
Our study about the unusual molecular mechanism behind the antibiotic activity of teixobactin can be read open access here:
https://www.nature.com/articles/s41586-022-05019-y
Figure: The target of teixobactin are bacteria-specific molecules (e.g. they do not exist in human cells) in outer membranes of bacteria. Teixobactin sits on the membrane and aggregates into fibrils, damaging the bacterial membrane and hindering its functions. We got these images by atomic force microscopy that has nanometer resolution. We can see individual teixobactin molecules coming to the bacterial membrane and forming the aggregate.
This is the first star from my research on antibiotics that I started at my postdoc in the Netherlands. More are coming out soon! The very first star was published in Nature, the most read journal in life sciences. I am in scientific heaven!
"So you navigate your life with the help of others who held mirrors up for you. People praised your good qualities and criticised your bad habits, and these perspectives -often surprising to you - helped you to guide your life.
So poorly did you know yourself that you were always surprised at how you looked at the photographs or how you sounded on the voice mail.
In this way, much of your existence took place in the eyes, ears and fingertips of others." - David Eagleman, Sum
Consciousness never "switches off" because it isn't generated by the brain. Its sensory inputs can be switched off - during sleep or general anesthesia, for instance - but your consciousness is still there. For example, a small but consistent number of patients report out-of-body experiences (OOBEs) or near-death experiences (NDEs) while under general anesthesia. As someone with REM Sleep Behavior Disorder (RBD) I can attest to this, since I act out dreams that occur during the non-REM phases of sleep.
Feels like summer 23.07.2024.
Wake up babe new aperiodic tiling dropped
Aperiodic tiling with only one tile!
Archaeologists believe that around 417 cities, towns, and villages made up the unified civilization.
Remains of architectural forms and patterns, ceramics, sculptural art, architectural patterns, and unifying causeway constructions.
The magnitude of the labor int he construction of massive platforms, palaces, dams, causeways, and pyramids dating to the Middle and Late Preclassic periods, suggests a power to organize thousands of workers.